Search results - 187 results
Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs.
J (2020) Abstract: Conventional molecular tests for detecting complex (MTBC) drug resistance on clinical samples cover a limited set of mutations. Whole genome sequencing (WGS) typically requires culture. ...
Use of a Whole Genome Sequencing-based approach for Mycobacterium tuberculosis surveillance in Europe in 2017-2019: an ECDC pilot study.
multi-drug resistant (MDR)-tuberculosis (TB) were collected from EU / EEA countries between January 2017 and December 2019. WGS-based genetic relatedness analysis was performed using a standardised approach ...
Decreasing and stabilising trends of antimicrobial consumption and resistance in and in segmented regression analysis, European Union/European Economic Area, 2001 to 2018.
EARS-Net Study Group Source: Euro Surveill, Volume 24, Issue 46 (2019) Keywords: Anti-Bacterial Agents antimicrobial stewardship Cephalosporins Drug Resistance, Multiple, Bacterial Drug Utilization ...
Diphtheria in Belgium: 2010-2017.
Denis Source: J Med Microbiol, Volume 68, Issue 10 (2019) Keywords: ADOLESCENT Adult Aged Aged, 80 and over Anti-Bacterial Agents Belgium Child, Preschool Corynebacterium Diphtheria Diphtheria Toxin Drug ...
Characterization and hazard identification of substandard and falsified antimicrobials encountered in Belgium
essential life-saving medicines could cause treatment failures, antimicrobial resistance and drug side effects [1]. Therefore, validated and robust analytical tools enabling the identification and ...
Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid
incidence and counter the spread of multidrug resistant TB, the discovery and characterization of new drugs is essential. In this study, the transcriptional response of two Mycobacterium tuberculosis strains ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
the knowledge on resistance mutations which is limited for especially 2nd-line and new drugs, (b) do not distinguish living from death cells, (c) ignore all intrinsic resistance mechanisms like efflux ...
Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing
susceptibility to first-line antituberculosis drugs has not been clear. METHODS: We obtained whole-genome sequences and associated phenotypes of resistance or susceptibility to the first-line antituberculosis ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
Pieter-Jan Ceyssens Source: 39th Annual Congress of the European Society of Mycobacteriology, Issue ESM, Dresden, Germany (2018) Keywords: drug susceptibility testing Mycobacterium tuberculosis Health Topics: ...
A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.
profiles; phenotypic resistance to isoniazid, rifampicin, ethambutol, pyrazinamide, and capreomycin; and corresponding drug resistance mutations. We whole-genome sequenced all Mycobacterium tuberculosis ...