Search results - 262 results
MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles
Mycobacteria. 34 clinical M. tuberculosis isolates were investigated for their resistance profile to four different drugs (rifampicin, isoniazid, ethambutol and linezolid), yielding a 100% concordance to the ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
recent report of the WHO ranks tuberculosis (TB) alongside HIV as a leading cause of death by infectious diseases. In combination, the spread of (multi-)drug resistant Mycobacterium tuberculosis is rising ...
Case report of a false positive result of the Xpert(®) MTB/RIF assay for rifampicin resistance in Mycobacterium tuberculosis complex.
positive for TB and positive for RIF resistance. Confirmatory molecular tests and the phenotypic drug susceptibility determination supported the diagnosis of TB but not RIF resistance. The patient was ...
Positive epistasis of major low-cost drug resistance mutations rpoB531-TTG and katG315-ACC depends on the phylogenetic background of Mycobacterium tuberculosis strains.
epidemic. Here we analysed the transmission capacity of these strains in the context of their phylogenetic background and drug resistance mutations. The study collection included all multidrug resistant (MDR) ...
Innate signaling by mycolate esters of the cell wall of Mycobacterium tuberculosis and relevance for development of adjuvants for subunit vaccines
socioeconomic conditions, the increased incidence of drug-resistant M.tuberculosis strains and the co-infection with HIV (a major risk factor for development of TB). Currently only one vaccine is available against TB, the ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
(TB) alongside HIV as a leading cause of death by infectious diseases. In combination, the spread of (multi-)drug resistant Mycobacterium tuberculosis is rising (480 000 new cases), impeding the ...
Public health risk of antimicrobial resistance transfer from companion animals.
Volume 72, Issue 4, p.957-968 (2017) Keywords: Animals bacteria Bacterial Infections Disease Transmission, Infectious Drug Resistance, Bacterial Humans Pets Risk Assessment Zoonoses Abstract: ...
Consensus numbering system for the rifampicin resistance-associated rpoB gene mutations in pathogenic mycobacteria.
length and nucleotide sequence vary between bacterial species, including mycobacteria. Mutations in the rpoB gene alter the structure of this protein and cause drug resistance. To describe the ...
Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Combined Species Identification and Drug Sensitivity Testing in Mycobacteria.
curve [AUC] of >0.015, relative growth [RG] of <0.5; see the text for details). Using these settings, MBT-ASTRA analyses returned 175/177 M. tuberculosis and 65/66 NTM drug resistance profiles which ...
Antimicrobial resistance surveillance in Escherichia coli by using normalized resistance interpretation.
p.1-7 (2016) Keywords: Animals Anti-Bacterial Agents Drug Resistance, Bacterial Escherichia coli Escherichia coli Infections Microbial Sensitivity Tests Swine Swine Diseases Abstract: OBJECTIVES: To ...