Search results - 7 results
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
5 known positive and 5 known negative test compounds for genotoxicity was evaluated. In addition, 2 compounds with debatable genotoxicity data were tested to explore how the qPCR array would classify these. ...
Coatings in food contact materials: Potential source of genotoxic contaminants?
use in FCM coatings has not (recently) been evaluated. Since detailed evaluation of all compounds is not feasible, a pragmatic approach was developed to identify substances with a potential concern for ...
(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.
based on the combination of multiple (quantitative) structure-activity relationship ((Q) SAR) tools. Non-evaluated substances used in printed paper and board food contact materials (FCM) were selected for ...
Printed paper and board food contact materials as a potential source of food contamination.
(77%) considered non-evaluated in terms of potential toxicity. Based on a preliminary study of their physicochemical properties, it is estimated that most of the non-evaluated single substances have the ...
Evaluation of the potential health risks of substances migrating from polycarbonate replacement baby bottles.
the potential migration risks associated with these alternative materials were investigated. First, all substances were evaluated for endocrine disruptive (ED) activity by using different existing lists ...
Study of the possible migration risks of food contact materials for children under 3 years
s) covering a wide variety in polarity and chemical functionality was chosen to evaluate the extraction efficiency of n-hexane, iso-octane, ethyl acetate (EtOAc)-n-hexane (1:1 and 1:3), MTBE and ...
Evaluation of the migration of chemicals from baby bottles under standardised and duration testing conditions.
microwave, sterilisation and dishwasher, on the migration of different contaminants was evaluated by means of duration tests. These results were compared with a reference treatment (filling five times with ...