Search results - 35 results

Urinary nicotine metabolites: usefulness as biomarkers of smoking status

and further to trans-3’-hydroxycotinine (HCOT) by the cytochrome P450 CYP2A6 enzyme. It has been demonstrated that the ratio of HCOT to COT is an index of CYP2A6 activity, thus a marker of nicotine ...

Para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis33991

J.Biol.Chem., Volume 288, Issue 32, Number 23456, p.23447- 23456 (2013) Keywords: 0 a acid Activity Agent Agents Aminosalicylic Acid an antagonists & inhibitors Antitubercular Agents article AS Bacterial ...

Induction of the specific allergic immune response is independent of proteases from the fungus Alternaria alternata.

p.907-17 (2013) Keywords: Alternaria Animals Cytokines Enzyme Activation Epitopes Female Hypersensitivity Lung mice Mice, Inbred BALB C Mice, Inbred C57BL Myeloid Differentiation Factor 88 Peptide Hydrolases ...

Serological and virological BVDV prevalence and risk factor analysis for herds to be BVDV seropositive in Belgian cattle herds.

Disease Cattle cross-sectional studies Diarrhea Viruses, Bovine Viral Enzyme-Linked Immunosorbent Assay Logistic Models prevalence Risk Factors Seroepidemiologic Studies Surveys and Questionnaires ...

Autophagy and phagocytosis-like cell cannibalism exert opposing effects on cellular survival during metabolic stress4383

conserved enzyme that maintains cellular energy balance, leads to activity-dependent degeneration in neuronal tissue. Here, we show that energy depletion in Drosophila AMPK mutants results in increased ...

An appetite for destruction: from self-eating to cell cannibalism as a neuronal survival strategy4382

a functional AMPK enzyme (AMP-activated protein kinase) and that suffer from severe metabolic stress. We further demonstrated that autophagy and AMPK are interconnected in a negative feedback loop that prevents ...

CYP3A5 and ABCB1 polymorphisms influence tacrolimus concentrations in peripheral blood mononuclear cells after renal transplantation.

prospective study investigated the effect of genetic polymorphisms in a biotransformation enzyme (CYP3A5) and a transporter protein (ABCB1) on tacrolimus (Tac) whole blood concentrations in renal ...

Oseltamivir-resistant influenza virus A (H1N1), Europe, 2007-08 season36834

Source: Emerg.Infect.Dis., Volume 15, Issue 4, Number 560, p.552- 560 (2009) Keywords: 0 2007 2008 a Activity acute Agent Agents antagonists & inhibitors Antiviral Agents article classification Clinical ...

1199G> A and 2677G> T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation.

1 Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System Drug Administration Schedule Gene Frequency Genotype Graft Rejection Humans Immunosuppressive Agents Linear Models Liver Liver Transplantation ...

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