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Para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis33991

inhibition of DHPS or mutation in DHFS prevents the formation of the antimetabolite, thereby conferring resistance to PAS. In addition, we identified a bifunctional enzyme (riboflavin biosynthesis protein ...

M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.

p.e76442 (2013) Keywords: Animals Bacterial Load BCG Vaccine Disease Models, Animal Enzyme-Linked Immunospot Assay Injections, Subcutaneous Interferon-gamma Interleukin-17 Lymph Nodes mice Mice, Inbred C57BL ...

Validation of a commercially available indirect ELISA using a nucleocapside recombinant protein for detection of Schmallenberg virus antibodies.

Animals Antibodies, Neutralizing Antibodies, Viral Bunyaviridae Infections Cattle Enzyme-Linked Immunosorbent Assay Europe Fluorescent Antibody Technique, Indirect Gene Expression Neutralization Tests ...

Clinical pattern characterization of cattle naturally infected by BTV-8.

(2013) Keywords: Animals Belgium Bluetongue Bluetongue virus Cattle Cattle Diseases Conjunctivitis, Viral Enzyme-Linked Immunosorbent Assay France Lethargy Nasal Mucosa Real-Time Polymerase Chain Reaction ...

Intra-host variation structure of classical swine fever virus NS5B in relation to antiviral therapy.

Substitution Animals Antiviral Agents Classical Swine Fever Classical swine fever virus Enzyme Inhibitors Genetic Variation Imidazoles Pyridines RNA Replicase Swine Viral Proteins Abstract: Classical swine fever ...

Induction of the specific allergic immune response is independent of proteases from the fungus Alternaria alternata.

p.907-17 (2013) Keywords: Alternaria Animals Cytokines Enzyme Activation Epitopes Female Hypersensitivity Lung mice Mice, Inbred BALB C Mice, Inbred C57BL Myeloid Differentiation Factor 88 Peptide Hydrolases ...

Efficacy of chimeric Pestivirus vaccine candidates against classical swine fever: protection and DIVA characteristics.

Volume 162, Issue 2-4, p.437-46 (2013) Keywords: Animals Antibodies, Viral Classical Swine Fever Classical swine fever virus Enzyme-Linked Immunosorbent Assay Injections, Intramuscular Palatine Tonsil ...

Large-scale cross-sectional serological survey of Schmallenberg virus in Belgian cattle at the end of the first vector season.

cross-sectional studies Enzyme-Linked Immunosorbent Assay Female Orthobunyavirus Seasons Seroepidemiologic Studies Serologic Tests Abstract: A cross-sectional survey was conducted in the Belgian cattle population ...

Serological and virological BVDV prevalence and risk factor analysis for herds to be BVDV seropositive in Belgian cattle herds.

Disease Cattle cross-sectional studies Diarrhea Viruses, Bovine Viral Enzyme-Linked Immunosorbent Assay Logistic Models prevalence Risk Factors Seroepidemiologic Studies Surveys and Questionnaires ...

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