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ELM-the Eukaryotic Linear Motif resource-2024 update.

structural and functional components of modular eukaryotic proteins. They are also the most abundant, especially when considering post-translational modifications. As well as being found throughout the cell as ...

Targeted Chromosomal Barcoding Establishes Direct Genotype-Phenotype Associations for Antibiotic Resistance in Mycobacterium abscessus.

function to each identified polymorphism. Thus, in this study, we developed a fast, robust, and reliable method to assign genotype-phenotype associations for putative antibiotic-resistant polymorphisms in . ...

Clinical Evolution and Disease Burden in Belgian Cystic Fibrosis Patients: effect of Newborn Screening?

Annual prevalence of bacterial infections was not different between the 3 patient groups at the predefined time points. Burden of therapy was lower for NBS during the first 2 years of life. Lung function ...

Clinical Evolution and Disease Burden in Belgian Cystic Fibrosis Patients: effect of Newborn Screening?

Annual prevalence of bacterial infections was not different between the 3 patient groups at the predefined time points. Burden of therapy was lower for NBS during the first 2 years of life. Lung function ...

Burden of infectious disease studies in Europe and the United Kingdom: a review of methodological design choices

times higher compared to that published between 2000 and 2014. Almost all studies (97%) estimated DALY s based on the incidence- and pathogen-based approach and without social weighting functions ...

Quantitative risk assessment of allergens leaching from menstrual hygiene products.

women might be unknowingly exposed to allergens. Given that vaginal mucosae lack the vital barrier function of the skin, skin allergens can easily penetrate and become systemically available and hence ...

The HLS19-COM-P, a new instrument for measuring communicative health literacy in interaction with ohysicians: development and validation in nine European countries

unidimensional partial credit Rasch model, obtained acceptable goodness-of-fit indices and high reliability. Two items tend to under-discriminate. Few items displayed differential item functioning (DIF) across ...

Optimization of Long-Acting Bronchodilator Dose Ratios Using Isolated Guinea Pig Tracheal Rings for Synergistic Combination Therapy in Asthma and COPD.

optimizing lung function. This provides an insight into more effective treatments. In this study, the LABA s formoterol fumarate dihydrate (FOR) and indacaterol maleate (IND) were each associated with ...

Residential green space in association with the methylation status in a CpG site within the promoter region of the placental serotonin receptor HTR2A

maternal green space exposure. Future research is needed to understand better how these epigenetic changes are related to functional modifications in the placenta and the consequent implications for ...

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