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Shifting national surveillance of Shigella infections toward geno-serotyping by the development of a tailored Luminex assay and NGS workflow.

observation spurred the development of an in silico workflow which extracts the Shigella serotype from Next-Generation Sequencing (NGS) data, taking into account gene functionality. Both tools will be ...

Global burden of intellectual disability resulting from dietary exposure to lead, 2015

estimates, default ranges were created for countries with no data which encompassed the values encountered elsewhere. Blood lead levels and IQ decrements were estimated using functions previously developed by ...

Asymptomatic bacteriuria in older adults: the most fragile women are prone to long-term colonization

drastically increased rates of ABU and especially long-term ABU. ABU was best predicted by a scale describing the functional independence of older adults. Conclusions: Institutionalized women with incontinence ...

Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid

delamanid. Remarkably, the most highly induced genes comprise poorly characterized genes for which functional characterization might hint to the target molecule(s) of delamanid and its exact mode(s) of action. ...

Estimating the Reliability of Low-Abundant Signals and Limited Replicate Measurements through MS2 Peak Area in SWATH

SWATH Replicates Analysis 2.0 template from Sciex is used to highlight that the relationship between the MS2 peak area and the variability can be described by a function. This functional relationship ...

Differences in antigenic sites and other functional regions between genotype A and G mumps virus surface proteins.

Publication Type: Peer reviewed scientific article Authors: Sigrid Gouma; Tessa Vermeire; Steven Van Gucht; Lennart Martens; Veronik Hutse; Jeroen Cremer; Paul A Rota; Geert Leroux-Roels; Marion Koopmans; Rob van Binnendijk; Elien Vandermarliere Source: S ...

Relationship between mold exposure, specific IgE sensitization, and clinical asthma: A case-control study.

investigation of the properties of Penicillium spp is recommended because its exposure was found to be associated with a more pronounced impairment of lung function. Health Topics:  Health and disease monitoring ...

Multivalent binding of herpesvirus to living cells is tightly regulated during infection.

sulfate both on model surfaces and on living cells. Our biophysical results, correlated with other techniques, show that the major envelope glycoprotein functions as a regulator of binding valency during ...

Measuring disability: a systematic review of the validity and reliability of the Global Activity Limitations Indicator (GALI).

studies (SHARE, EHIS) concluded that the odds of reporting participation restriction was higher in subjects with self-reported or observed functional limitations. In SHARE, the size of the Odds Ratio’s (OR ...

Distribution of HCV genotypes in Belgium from 2008 to 2015.

infections. Genotype 6 and 7 comprise the remaining <1%. Throughout the years, a stable distribution was observed for most genotypes. Only for genotype 5, a decrease as a function of the year of analysis was ...

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