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Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans
cellular functions and promiscuous targets for many viruses. The screening pipeline was applied to the influenza A virus (IAV) PB2 polymerase proteins of five strains representing different levels of ...
A new approach to define acceptance limits for hematology in external quality assessment schemes.
their corresponding assigned value (U-scores) was modeled by means of an adaptation of Thompson’s “characteristic function”. Quantile regression was used to investigate the percentiles of the U-scores for ...
Multinomial additive hazard model to assess the disability burden using cross-sectional data.
attribution method to multinomial responses, since disability is often measured as a multicategory variable in most surveys, representing different severity levels. The R function constrOptim is used to ...
What can the CF registry tell us about rare CFTR-mutations? A Belgian study.
Abstract: BACKGROUND: CFTR2 provides clinical and functional information of the most common CFTR-mutations. Rare mutations (RM s) occur in only a few patients with limited reported clinical data. Their role ...
Effect of allergic bronchopulmonary aspergillosis on FEV1 in children and adolescents with cystic fibrosis: a European Cystic Fibrosis Society Patient Registry analysis.
function, the difference in FEV1 between young patients with and without the complication was found to be modest when the effect of other prognostic factors was considered. Health Topics: Quality of ...
Augmented and doubly robust G-estimation of causal effects under a Structural nested failure time model.
uncensored observations, and offers robustness against misspecification of the model for the censoring process, provided that a model for a specific functional of the survival time and time-dependent ...
Mapping EQ-5D utilities to GBD 2010 and GBD 2013 disability weights: results of two pilot studies in Belgium.
attributed a relatively higher severity level to musculoskeletal disorders such as ‘Amputation of both legs’ and a relatively lower severity level to non-functional disorders such as ‘Headache migraine’ ...
Ethnicity impacts the cystic fibrosis diagnosis: A note of caution.
patients with CF do not have a worse clinical phenotype. The repeatedly reported lower FEV1 of Asian patients with CF is attributable to the influence of ethnicity on lung function in general. However, ...
Invasion by the Alien Tree Alters Ecosystem Functions in a Temperate Deciduous Forest
impacts on ecosystem structure, function, and services.is a widespread invader of European temperate forests, where it tends to form homogeneous stands and limits recruitment of indigenous trees. We ...
Historical aspects of iodine deficiency control.
functional). A randomized clinical trial in Congo (RD) in the 1970’s also showed that correcting severe iodine deficiency during pregnancy prevents myxœdematous cretinism, particularly prevalent in affected ...