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Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs.

discordances involved gene deletions/indels and 3-12% heteroresistant calls undetected by WGS analysis, or natural pyrazinamide resistance of globally rare ” strains then unreported by Deeplex Myc- TB. On 1494 ...

Shifting national surveillance of Shigella infections toward geno-serotyping by the development of a tailored Luminex assay and NGS workflow.

a Shigella-specific deletion in the spermidine acetyltransferase gene speG, reflecting its metabolic decay. For Shigella serotype prediction, the multiplex assay scored a sensitivity and specificity of 96.6% and 98.4%, ...

Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.

proinflammatory gene expression and infiltration and activation of immune cells in brain. Specific deletion of in T cells also delayed disease development while deletion in myeloid cells, neuronal cells or NK cells ...

Detection and discrimination of five E. coli pathotypes using a combinatory SYBR® Green qPCR screening system

case of deletion or polymorphisms in the target gene. Moreover, all the qPCR have been designed to be run together in a single analytical PCR plate. This study includes the primer pairs' design, in ...

Construction of Nontoxigenic Mutants of Nonproteolytic Clostridium botulinum NCTC 11219 by Insertional Mutagenesis and Gene Replacement.

p.3100-3108 (2016) Keywords: Botulinum Toxins Clostridium botulinum type E Gene Deletion Hazard Analysis and Critical Control Points Hot Temperature Mutagenesis, Insertional Recombination, Genetic Sodium ...

Deletion of Murid Herpesvirus 4 ORF63 Affects the Trafficking of Incoming Capsids toward the Nucleus.

5, p.2455-72 (2015) Keywords: Animals Biological Transport Capsid Cell Line Cricetinae Female Gene Deletion Herpesviridae Infections Histocytochemistry Lung Mice, Inbred BALB C Rhadinovirus Viral ...

SYBR®Green qPCR Salmonella detection system allowing discrimination at the genus, species and subspecies levels.

highlighted the importance of using a multi-gene detection system to be able to detect every target strain, even those with deletion or mutation of important genes. Health Topics:  Food consumption and food ...

Severe acute cardiomyopathy associated with venlafaxine overdose and possible role of CYP2D6 and CYP2C19 polymorphisms.

Gene Deletion Half-Life Heart Failure Humans Milrinone Norepinephrine Polymorphism, Genetic Serotonin Uptake Inhibitors Venlafaxine Hydrochloride Abstract: INTRODUCTION: Venlafaxine (VEN) is ...

Antifungal activity displayed by cereulide, the emetic toxin produced by Bacillus cereus

food Fungi Gene Deletion Genes,Bacterial growth & development im IS journal Laboratories metabolism Microbial Sensitivity Tests microbiology pharmacology Plasmids Research Research Support Role SB- ...

The bovine herpesvirus 4 Bo10 gene encodes a nonessential viral envelope protein that regulates viral tropism through both positive and negative effects.

Laurent Source: J Virol, Volume 85, Issue 2, p.1011-24 (2011) Keywords: Animals Cattle Cell Line Epithelial Cells Gene Deletion Herpesvirus 4, Bovine Molecular Weight Proteome Viral Envelope Proteins Viral ...

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