Search results - 21 results

The lack of K13-propeller mutations associated with artemisinin resistance in Plasmodium falciparum in Democratic Republic of Congo (DRC).

Democratic Republic of the Congo Drug Resistance Female Humans Malaria, Falciparum Male middle aged Mutation Plasmodium falciparum Polymorphism, Genetic Young adult Abstract: Artemisinin-based combination ...

Collaborative data collection by TREAT-NMD Registries to support post-marketing surveillance in Spinal Muscular Atrophy

Spinal muscular atrophy (SMA) is a rare genetic neuromuscular disorder characterized by a loss of motor neurons in the spinal cord and the brainstem, leading to muscle weakness and atrophy. The estimated ...

Molecular surveillance of Plasmodium falciparum resistance to artemisinin-based combination therapies in the Democratic Republic of Congo.

Benoit-Vical, Françoise; Melin, Pierrette; De Mol, Patrick; Hayette, Marie-Pierre Source: PLoS One, Volume 12, Issue 6 (2017) Keywords: Artemisinins Democratic Republic of the Congo Drug Resistance Drug Therapy ...

The TREAT-NMD DMD Global Database: analysis of more than 7,000 Duchenne muscular dystrophy mutations

Databases Development Diagnostics disease Diseases Duchenne muscular dystrophy electronic Frequency Genetic Genetic Therapy global im Institute IS journal Medicine Muscular Dystrophies Muscular dystrophy ...

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.

poliovirus, coxsackievirus, rhinovirus, and enterovirus 71) for which no antiviral drugs are available. The viral RNA-dependent RNA polymerase is an attractive target for antiviral therapy. Nucleoside-based ...

New challenges in perioperative management of pancreatic cancer.

Devière, Jacques; Van Laethem, Jean-Luc Source: World J Gastroenterol, Volume 21, Issue 8 (2015) Keywords: Biomarkers, Tumor Carcinoma, Pancreatic Ductal Chemotherapy, Adjuvant Humans Neoadjuvant Therapy ...

Engineering nucleases for gene targeting: safety and regulatory considerations.

(2014) Keywords: Deoxyribonucleases Gene Targeting Genetic Therapy Humans SAFETY Abstract: Nuclease-based gene targeting (NBGT) represents a significant breakthrough in targeted genome editing since it is ...

General considerations on the biosafety of virus-derived vectors used in gene therapy and vaccination.

p.385-94 (2013) Keywords: Animals Clinical Trials as Topic Genetic Therapy Genetic Vectors Hazardous Substances Humans Organisms, Genetically Modified Risk Assessment Vaccination Viruses Abstract: This ...

Biosafety of viral vectors commonly used in gene therapy and vaccination.

Publication Type: Peer reviewed scientific article Authors: Philippe Herman Source: Curr Gene Ther, Volume 13, Issue 6, p.383-4 (2013) Keywords: Genetic Therapy Genetic Vectors Hazardous Substances ...

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