Search results - 6 results
The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.
resistance, or consistent with susceptibility, for 13 WHO endorsed anti-tuberculosis drugs. 38,215 MTBC isolates with paired whole-genome sequencing and phenotypic drug susceptibility testing data were amassed ...
Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.
Organization priority. We previously developed a software tool,, which provided offline species identification and drug resistance predictions for from whole genome sequencing (WGS) data. Performance was ...
A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.
profiles; phenotypic resistance to isoniazid, rifampicin, ethambutol, pyrazinamide, and capreomycin; and corresponding drug resistance mutations. We whole-genome sequenced all Mycobacterium tuberculosis ...
Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection
also associated with progressive suppression of IFN-γ and IL-17 responses, and increased IL-10 production. Whole genome sequencing of the two virulent isolates with MST22 genotype and two avirulent ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
(480 000 new cases), impeding the treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations. ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations. However, transcriptional analyses can be ...