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Characterisation of tetanus monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay.
Batch release testing for human and veterinary tetanus vaccines still relies heavily on methods that involve animals, particularly for potency testing. The quantity and quality of tetanus antigen present ...
Characterisation of diphtheria monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay.
having been specifically developed as alternatives to in vivo potency tests. These methods require at least one well characterised monoclonal antibody (mAb) that is specific for the target antigen. In this ...
Regulatory issues regarding manufacture and control of vaccine adjuvants. The EU situation.
components that potentiate the immune responses to an antigen and/or modulate it towards the desired immune responses. Adjuvants can be classified according to their source, mechanism of action, or physical or ...
Differences in Antigenic Structure of Inactivated Polio Vaccines Made From Sabin Live-Attenuated and Wild-Type Poliovirus Strains: Impact on Vaccine Potency Assays.
Alexandre Dobly Source: J Infect Dis, Volume 221, Issue 4 (2020) Keywords: Antibodies, Neutralizing Antibodies, Viral Antigens, Viral Humans Immunogenicity, Vaccine Poliomyelitis Poliovirus Poliovirus ...