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Isolation and characterization of the compounds responsible for the antimutagenic activity of Combretum microphyllum (Combretaceae) leaf extracts

scavenging method. The cytotoxicity was determined in the MTT assay using human hepatocytes. RESULTS: A bioassay-guided fractionation of the crude extracts for antimutagenic activity led to the isolation of ...

Genotoxicity testing of 3,4,5-trimethylfuran-2(5H)-one, a compound from plant-derived smoke with germination inhibitory activity.

Environ Mutagen, Volume 778, p.1-5 (2015) Keywords: 4-Nitroquinoline-1-oxide Benzopyrenes Cell Line, Tumor Cell Survival Furans Genes, Reporter Germination Hepatocytes Humans Luciferases Mutagenicity Tests ...

Synthesis and antimycobacterial activity of analogues of the bioactive natural products sampangine and cleistopholine36497

against C3A hepatocytes, the therapeutic index showed an acceptable range. Further tests confirmed the inhibition by up to 74% of intracellular growth of M.tb inside macrophages conferred by ...

Biological evaluation of bisbenzaldehydes against four Mycobacterium species.

Dose-Response Relationship, Drug Drug Resistance, Bacterial Hepatocytes Host-Pathogen Interactions Humans Macrophages mice Microbial Sensitivity Tests Molecular Structure Mycobacterium Mycobacterium avium ...

Straightforward palladium-mediated synthesis and biological evaluation of benzo[j]phenanthridine-7,12-diones as anti-tuberculosis agents

effective electronic EVALUATION growth health Hepatocytes Human im immunology Infectious diseases Institute IS journal M Macrophages Mycobacterium Mycobacterium tuberculosis ON pathogen public public health ...

Kinetic and biologic properties of recombinant ChIFN-gamma expressed via CELO-virus vector.

vector was able to replicate in vitro in the loghorn male hepatoma (LMH) hepatocyte cell line and to produce detectable levels of recombinant cytokine in supernatant as early as 90 min post-infection. ...

Differential inlA and inlB expression and interaction with human intestinal and liver cells by Listeria monocytogenes strains of different origins36774

a number of Listeria monocytogenes strains of different origins were evaluated for in vitro invasion capacity for various human cell types (monocytic THP-1, enterocytic Caco-2, and hepatocytic HepG2 cells) ...

Naturally-occurring Tyzzer's disease (Bacillus piliformis infection) in commercial rabbits: a clinical and pathological study.

PAS- and silver-positive rod-shaped bacilli were established in apparently viable hepatocytes bordering foci of necrosis. They were also present in myocytes around necrotic foci in the heart and in ...

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