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Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection

liver and mycobacteria specific spleen cell IFN-γ, IL-10 and IL-17 production as well as serum antibody responses were analyzed. Isolates varied in virulence, with human and porcine isolates sharing MST22 ...

Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection.

liver and mycobacteria specific spleen cell IFN-γ, IL-10 and IL-17 production as well as serum antibody responses were analyzed. Isolates varied in virulence, with human and porcine isolates sharing MST22 ...

Inflammatory Properties and Adjuvant Potential of Synthetic Glycolipids Homologous to Mycolate Esters of the Cell Wall of Mycobacterium tuberculosis.

(TMM, GMM, and AraMM) activate bone marrow-derived dendritic cells in terms of the production of pro-inflammatory cytokines (IL-6 and TNF-α) and reactive oxygen species, upregulation of costimulatory ...

Innate signaling by mycolate esters of the cell wall of Mycobacterium tuberculosis and relevance for development of adjuvants for subunit vaccines

similar immune responses characterized by a production of antigen-specific IFN-γ and IL-17A. The immune responses induced by AraMM are dependent on the type of formulation. Indeed, AraMM in emulsion does ...

Modulation de l’activité transcriptionelle de récepteurs nucléaires par les produits de migration de matériaux en plastique destinés aux jeunes enfants

perturbateur endocrinien avéré, puisqu’il existe des preuves d’une activité in vivo de perturbateur endocrinien sur au moins une espèce, en utilisant des animaux intacts. Sur base de la classification des 17 ...

CCR2(+)CD103(-) intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells.

(IL)-17a production by T cells in vitro, and show constitutive expression of IL-12/ IL-23p40. These data highlight the heterogeneity of intestinal DC s and reveal a bona fide population of CCR2 (+) DC s that ...

Mice genetically inactivated in interleukin-17A receptor are defective in long-term control of Mycobacterium tuberculosis infection.

IL-17A receptor signalling in immune defence against this intracellular pathogen remains poorly documented. Here we have analysed this signalling using C57BL /6 mice genetically inactivated in the IL-17 ...

Mucosal and systemic immune responses to Mycobacterium tuberculosis antigen 85A following its co-delivery with CpG, MPLA or LTB to the lungs in mice1377

Keywords: a Antigens Cell cells challenge enterotoxin Escherichia coli IL-17A immune response Immunization INFECTION Inflammation IS IT LEVEL levels Lipid A Lung M mice Mycobacterium Mycobacterium ...

M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.

Th1 (IFN-γ, IL-2 and TNF-α) and IL-17 responses could be induced following subcutaneous vaccination with either of the two mutants, than following vaccination with M. bovis BCG. Significantly more ...

Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary delivery34028

Brussels Cell cells Cells,Cultured Combination Cytokines de delivery DRUG Drug Delivery Systems drug effects electronic factors Female Group IL-17A im immune response Immunity,Cellular immunology Increase ...

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