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Advanced Methods for Dose and Regimen Finding During Drug Development: Summary of the EMA/EFPIA Workshop on Dose Finding (London 4-5 December 2014).

models, quantitative systems pharmacology models, MCP-Mod, and model averaging) and three methods for study design optimization (Fisher information matrix (FIM)-based methods, clinical trial simulations, ...

Commentary on the MID3 Good Practices Paper.

Model-Informed Drug Discovery and Development (MID3) group in promoting greater consistency in practice, application, and documentation of M&S and considers the paper is an important contribution towards ...

Fusarium, clinical relevance and mass spectrometry methods for identification, using strains of the Belgian fungal culture collection BCCM/IHEM

strain information revealed a species, i.e. Fusarium musae, of which it was not yet known that it caused human infections. (ii) A new species, closely related to Fusarium, was described, i.e. ...

Dietary exposure to pyrrolizidine alkaloids in young children and adults from the Belgian population (PASFOOD)

additieven Organic contaminants and additives Information sanitaire Gezondheidsinformatie Health information Éléments traces et nanomatériaux Spoorelementen en nanomaterialen Trace elements and nanomaterials ...

World Health Organization estimates of the relative contributions of food to the burden of disease due to selected foodborne hazards: A structured expert elicitation

ability to judge uncertainty accurately and informatively using a series of subject-matter specific ‘seed’ questions whose answers are unknown to the experts at the time they are interviewed. Trained ...

Measurement equivalence of the Belgian health interview auto-questionnaire: paper-based versus web-based mode.

la santé et des maladies Ziekten en gezondheid in kaart brengen Service:  Information sanitaire Gezondheidsinformatie Health information Full text language:  English Category:  C31 FOS Classification:  ...

An integrated and sustainable EU health information system: national public health institutes' needs and possible benefits.

data and health information are at the basis of evidence-based policy-making and research, still no single, integrated and sustainable EU-wide public health monitoring system or health information ...

Registration of treatment demands for substance use disorders in Belgium: Why are some clients registered anonymously?

illégales Service:  Information sanitaire Gezondheidsinformatie Health information Manuscript versions:  File:  Version:  Published Full text access:  Public Access Full text language:  English Category:  ...

Imported human brucellosis in Belgium: Bio and molecular typing of bacterial isolates, 1996-2015.

associated to each biovar, but it allowed retrieving precious epidemiological information. The analysis highlighted the imported nature of the strains from all over the world with a dominant part from the ...

Strain- and Dose-Dependent Reduction of Toxoplasma gondii Burden in Pigs Is Associated with Interferon-Gamma Production by CD8(+) Lymphocytes in a Heterologous Challenge Model.

parasite in the tissues. Hence, experimental infections in pigs can provide more information on the risk for zoonosis based on the parasite burden in meat products intended for human consumption and on the ...

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