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Lumpy Skin Disease Is Characterized by Severe Multifocal Dermatitis With Necrotizing Fibrinoid Vasculitis Following Experimental Infection.

Diseases, Emerging Dermatitis Endemic Diseases Europe Lumpy skin disease Lumpy skin disease virus SKIN Vasculitis Abstract: Lumpy skin disease is a high-consequence disease in cattle caused by infection with ...

Cytokine and immunoglobulin isotype profiles during CP7_E2alf vaccination against a challenge with the highly virulent Koslov strain of classical swine fever virus.

Vaccination Vaccines, Attenuated Viral Vaccines Abstract: CP7_E2alf is a promising marker vaccine candidate against classical swine fever (CSF). To better understand the mechanisms of protection, cytokine and ...

Towards a typing strategy for Arcobacter species isolated from humans and animals and assessment of the in vitro genomic stability.

species. With a limited number of isolates to be characterized, PFGE with restriction by KpnI is proposed as the first method of choice. However, ERIC- PCR represents a more convenient genomic fingerprinting ...

Sustained stimulation and expansion of Tregs by IL2 control autoimmunity without impairing immune responses to infection, vaccination and cancer.

Factors Vaccination Abstract: Interleukin 2 (IL2) is the key cytokine supporting survival and function of regulatory T cells (Tregs). We recently reported that low-dose IL2 safely expands/stimulates Tregs ...

Bluetongue, Schmallenberg- what is next? Culicoides-borne viral diseases in the 21st Century.

Publication Type: Peer reviewed scientific article Authors: Koenraadt, Constantianus Jm; Balenghien, Thomas; Carpenter, Simon; Ducheyne, Els; Elbers, Armin Rw; Fife, Mark; Garros, Claire; Ibáñez-Justicia, Adolfo; Kampen, Helge; Kormelink, Richard Jm; Loss ...

Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.

picornaviral polyprotein is essential for viral replication. Therefore, viral proteases are attractive targets for anti-viral therapy. Most assays available for testing proteolytical activity of proteases are ...

Efficacy of marker vaccine candidate CP7_E2alf against challenge with classical swine fever virus isolates of different genotypes.

Vaccination Vaccines, Marker Vaccines, Synthetic Viral Vaccines Abstract: Classical swine fever (CSF) is among the most important viral disease of domestic and feral pigs and has a serious impact on animal ...

Genotoxicity evaluation of nanosized titanium dioxide, synthetic amorphous silica and multi-walled carbon nanotubes in human lymphocytes.

characterization of manufactured nanomaterials (NM s) is essential for safety assessment, while keeping pace with innovation from their development and application in consumer products. The specific physicochemical ...

Coupling of drug containing liposomes to microbubbles improves ultrasound triggered drug delivery in mice.

Local extravasation and triggered drug delivery by use of ultrasound and microbubbles is a promising strategy to target drugs to their sites of action. In the past we have developed drug loaded ...

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