Search results - 5 results
Deepening of In Silico Evaluation of SARS-CoV-2 Detection RT-qPCR Assays in the Context of New Variants
Keersmaecker Source: Genes, Volume 12, Issue 4 (2021) Keywords: SARS-CoV-2; COVID-19; variants; detection; RT-qPCR; in silico specificity evaluation; bioinformatics tool; WGS data; mismatches; primers and probes ...
Identification of flavouring substances of genotoxic concern present in e-cigarette refills
establish a screening strategy to prioritize the flavouring substances of highest concern for human health. In the present study, a prioritization strategy combining analytical screening, in silico tools and ...
Chemical and toxciological characterization of e-liquid cigarettes
quantitative in silico models. In total, potential genotoxicity activity was predicted for 44 flavourings. Based on information from European databases, genotoxicity could be confirmed for five of these ...
Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.
RT-qPCR methods were developed in January 2020 for initial in silico specificity evaluation and to verify whether the targeted loci are highly conserved. Now that more whole genome data have become ...
Identification of Flavouring Substances of Genotoxic Concern Present in E-Cigarette Refills
cancer. Therefore, in this study, a prioritization strategy based on a combination of analytical screening, in silico prediction and literature consultation was developed for identifying potentially ...