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In Vivo Kinetics and Biotransformation of Aflatoxin B1 in Dairy Cows Based on the Establishment of a Reliable UHPLC-MS/MS MethodDataSheet1.docx

in plasma (0.5 ± 0.1 ng ml−1) at 4 h after the ingestion. AFB1  was found in the heart, spleen, lungs, and kidneys at concentrations of 1.6 ± 0.3, 4.1 ± 1.2, 3.3 ± 0.9 and 5.6 ± 1.4 μg kg−1, ...

Risk assessment of ochratoxin A in food

ochratoxin A (OTA) in food. OTA is produced by fungi of the genus Aspergillus and Penicillium and found as a contaminant in various foods. OTA causes kidney toxicity in different animal species and kidney ...

Risk assessment of chlorinated paraffins in feed and food

paraffins in feed and food. The data for experimental animals were reviewed and the CONTAM Panel identified the liver, kidney and thyroid as the target organs for the SCCP and MCCP mixtures tested in repeated ...

Estimates of the 2015 global and regional disease burden from four foodborne metals- arsenic, cadmium, lead and methylmercury

ingestion of cadmium is causally associated with an increased risk of late stage chronic kidney disease. This article presents an overview of the burden of disease from these four foodborne metals and ...

Global burden of late-stage chronic kidney disease resulting from dietary exposure to cadmium, 2015

Keywords: Cadmium Chronic kidney disease Diet Disability-adjusted life year Foodborne burden of disease Abstract: Chronic exposures to cadmium (Cd) are associated with reduced glomerular filtration rate ...

Welfare-Adjusted Life Years (WALY): A novel metric of animal welfare that combines the impacts of impaired welfare and abbreviated lifespan.

lifespan at the time of premature death. To demonstrate the concept, we estimated WALY s for 10 common canine diseases, namely mitral valve disease, dilated cardiomyopathy, chronic kidney disease, diabetes ...

UPLC-MS/MS analysis of antibiotics in pharmaceutical effluent in Tunisia: ecotoxicological impact and multi-resistant bacteria dissemination

38 and 22% for concentrated sample (10×) and non-concentrated sample (1×), respectively. However, the histological sections of kidney and liver’s mice treated by pharmaceutical effluent showed normal ...

Attenuation of RNA viruses by redirecting their evolution in sequence space.

Darby Canine Kidney Cells Orthomyxoviridae Infections Point Mutation virulence Abstract: RNA viruses pose serious threats to human health. Their success relies on their capacity to generate genetic ...

Us3 and Us9 proteins contribute to the stromal invasion of bovine herpesvirus 1 in the respiratory mucosa.

(latitude) in Madin-Darby bovine kidney (MDBK) cells and the respiratory mucosa as well as viral penetration depth underneath the BM of the respiratory mucosa when inoculated with these recombinant viruses. ...

Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.

Humans Kidney Tubules, Proximal Laboratory Proficiency Testing Liver Observer Variation Oligonucleotide Array Sequence Analysis Reproducibility of Results Risk Assessment Time Factors Toxicogenetics ...

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