Search results - 8 results

Multicentre study on the reproducibility of MALDI-TOF MS for nontuberculous mycobacteria identification.

was obtained for 100% of isolates in 5 laboratories (68.2-98.6% in the other). Species-level identification provided by MALDI- TOF was 100% correct in 8 centres and 100% correct to complex-level in 12 ...

Strong increase of true and false positive mycobacterial cultures sent to the National Reference Centre in Belgium, 2007 to 2016.

Mathys Source: Euro Surveill, Volume 24, Issue 11 (2019) Abstract: IntroductionIn 2007, a new federal legislation in Belgium prohibited non-biosafety level 3 laboratories to process culture tubes suspected ...

Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection

of the mammalian cell entry family, that were identical with Mah 104 strain. Despite the obvious limitations of the mouse model, a striking link of virulence and identity at the genome level of porcine ...

MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

cultures. In total 88.6% (172/194) of the samples were correctly identified on the species-level using a cut-off score of 1.8 and 91.75% (178/194) using a cut-off of 1.65. All samples of the Mycobacterium ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

(480 000 new cases), impeding the treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations. ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations. However, transcriptional analyses can be ...

WIV-ISP's experiences in the use of MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

Mycobacteria and their drug resistance profiles. By using an optimized extraction protocol, they successfully identified 88.14 % of 194 Mycobacterial strains at a species-level and 3.09 % at genus-level, using ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

Fisher) technology. The normalized expression levels are combined to one numeric value which determines the drug susceptibility of the investigated strain. Results We successfully developed 8 primary sets ...

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