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Worldwide burden of cervical cancer in 2008.

<1 to > 50 per 100,000. Cervical cancer is the leading cause of cancer-related death among women in Eastern, Western and Middle Africa; Central America; South-Central Asia and Melanesia. The highest ...

Toxicokinetics of cocaine and metabolites in a body-packer becoming symptomatic.

cocaine may lead to fatality. We report the case of a 35-year-old body-packer who developed at the airport clinical signs of cocaine toxicity. There was evidence of bowel obstruction. The plasma ...

Severe acute cardiomyopathy associated with venlafaxine overdose and possible role of CYP2D6 and CYP2C19 polymorphisms.

a complete deletion of CYP2D6  gene. CONCLUSIONS: Severe and sustained cardiotoxicity following VEN overdose may be related to the amount ingested, as well as to the genetic polymorphism for CYP2D6 leading to ...

Tea brewed in traditional metallic teapots as a significant source of lead, nickel and other chemical elements.

Assess, Volume 28, Issue 9, p.1287-93 (2011) Keywords: Food Contamination Food Packaging Lead Nickel Tea Abstract: An environmental inquiry conducted by the Brussels Inter-communal Laboratory of Chemistry ...

Heterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, β-cell proliferation, and mass.

exchanger leads to an increase in β-cell function, proliferation, mass, and resistance to physiologic stress, namely to various changes in β-cell function that are opposite to the major abnormalities seen in ...

Novel norovirus recombinants and of GII.4 sub-lineages associated with outbreaks between 2006 and 2010 in Belgium36558

purification journal Lead Medicine Molecular Sequence Data Mutation n Norovirus observed Order outbreak outbreaks Patient patients pattern PATTERNS period recombinant recombination Recombination,Genetic Research ...

Experimental tuberculosis in the Wistar rat: a model for protective immunity and control of infection36574

epithelioid cells, multinucleated giant cells and foamy macrophages surrounded by large numbers of lymphocytes. The late stage subclinical form of disease was reactivated by immunosuppression leading to ...

Guidelines for Independent Lot Release of Vaccines by Regulatory Authorities

BCG conditions consultation Control Countries criteria data Decision function guidance Guidelines health HPV IS IT Laboratories Lead marketing measurement national need ON PRODUCTS PROGRAM programme ...

Development of a foot-and-mouth disease infection model in severe combined immunodeficient mice for the preliminary evaluation of antiviral drugs.

early antiviral lead molecules with anti-foot-and-mouth disease virus (FMDV) activity in vitro. In a first attempt, several FMDV strains were titrated in Balb/c mice. Inoculations with O₁ Manisa or C₁ ...

Implementation over the past 20 years of the 3R's principle for batch release at the Scientific Institute of Public Health, Belgium (IPH).

toxoid vaccines, the multiple dilution assay was replaced by a single dilution assay, based on historical data, leading to a threefold reduction in the amount of animals used. The same reduction scheme has ...

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