Search results - 11 results

Laboratory validation of two real-time RT-PCR methods with 5'-tailed primers for an enhanced detection of foot-and-mouth disease virus.

Publication Type: Peer reviewed scientific article Authors: VandenBussche, Frank; David Lefebvre; Ilse De Leeuw; Van Borm, Steven; Kris De Clercq Source: J Virol Methods, Volume 246, p.90-94 (2017) ...

A Tale of Tails: Dissecting the Enhancing Effect of Tailed Primers in Real-Time PCR.

Publication Type: Peer reviewed scientific article Authors: VandenBussche, Frank; Mathijs, Elisabeth; Lefebvre, David; Kris De Clercq; Van Borm, Steven Source: PLoS One, Volume 11, Issue 10, ...

A Refined Guinea Pig Model of Foot-and-Mouth Disease Virus Infection for Assessing the Efficacy of Antiviral Compounds.

Publication Type: Peer reviewed scientific article Authors: Annebel De Vleeschauwer; David Lefebvre; Willems, T; Paul, G; Billiet, A; Murao, L E; Neyts, J; Goris, N; Kris De Clercq Source: ...

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.

Palma, Armando M; Tanchis, Federica; Goris, Nesya; Lefebvre, David; Kris De Clercq; Leyssen, Pieter; Lacroix, Céline; Pürstinger, Gerhard; Coutard, Bruno; Canard, Bruno; Boehr, David D; Arnold, Jamie J; ...

A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus.

Publication Type: Peer reviewed scientific article Authors: David Lefebvre; Annebel De Vleeschauwer; Goris, Nesya; Van Borm, Steven; Chimirri, Alba; Monforte, Anna Maria; Valdazo-Gonzalez, Begona; ...

Proof of concept for the inhibition of foot-and-mouth disease virus replication by the anti-viral drug 2'-C-methylcytidine in severe combined immunodeficient mice.

Publication Type: Peer reviewed scientific article Authors: David Lefebvre; Annebel De Vleeschauwer; Goris, N; Kollanur, D; Billiet, A; Murao, L; Neyts, J; Kris De Clercq Source: Transbound Emerg ...

In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.

Publication Type: Peer reviewed scientific article Authors: Osiceanu, Ana-Maria; Murao, Lyre Espada; Kollanur, Denny; Swinnen, Jan; Annebel De Vleeschauwer; David Lefebvre; Kris De Clercq; Neyts, ...

Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.

Lefebvre, David; Lanke, Kjerstin H W; Kris De Clercq; Hilgenfeld, Rolf; Neyts, Johan; van Kuppeveld, Frank J M Source: Antiviral Res, Volume 103, p.17-24 (2014) Keywords: Animals Antiviral Agents Cell Line ...

Characteristics of serology-based vaccine potency models for foot-and-mouth disease virus.

Publication Type: Peer reviewed scientific article Authors: Willems, Tom; David Lefebvre; Goris, Nesya; Diev, Vyacheslav I; Kremenchugskaya, Svetlana R; Paul, Guntram; Haas, Bernd; Kris De Clercq ...

Diagnostic performance and application of two commercial cell viability assays in foot-and-mouth disease research.

Publication Type: Peer reviewed scientific article Authors: Willems, Tom; David Lefebvre; Neyts, Johan; Kris De Clercq Source: J Virol Methods, Volume 173, Issue 1, p.108-14 (2011) Keywords: Animals ...

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