Search results - 44 results
A roadmap for regulatory implementation of in vitro models for evaluation of vaccine efficacy
Publication Type: Scientific poster, presentation or proceeding Authors: R. J. Vandebriel; L. Tesolin; K. Veenstra; K. Huber Source: EVI, Niagara falls, Canada (2023) Keywords: in vitro model ...
Spectroscopic approaches for conformity analysis of e-liquids
modelling. Next to baseline correction, classical preprocessing techniques like standard normal variate (SNV), derivatives and scaling were explored. In a first step, supervised modelling, using partial least ...
Homologous versus heterologous prime-boost COVID-19 vaccination: impact on clinical severity of Omicron among hospitalized COVID-19 patients in Belgium
the study population. An adjusted logistic model was build and g-computation was executed to estimate counterfactual risks of different clinical severity outcomes (intensive care unit (ICU) transfer, ...
Potential business model for a European vaccine R&D infrastructure and its estimated socio-economic impact
Publication Type: Peer reviewed scientific article Authors: Jungbluth, Stefan; Martin, William; Slezak, Monika; Depraetere, Hilde; Guzman, Carlos A.; Ussi, Anton; Morrow, David; Van Heuverswyn, Fran; Arnouts, Sven; Carrondo, Manuel J. T.; Olesen, Ole; Ott ...
Vaccine effectiveness against onward transmission of SARS-CoV2-infection by variant of concern and time since vaccination, Belgian contact tracing, 2021.
infectiousness of breakthrough cases (VE i) for a complete schedule of Ad26. COV2.S, ChAdOx1, BNT162 b2, mRNA-1273 as well as infection-acquired and hybrid immunity. We used a multilevel Bayesian model and ...
Incidence and Risk Factors of COVID-19 Vaccine Breakthrough Infections: A Prospective Cohort Study in Belgium.
associated with breakthrough infections were analyzed using COX proportional hazard models. Among 8,062,600 fully vaccinated adults, we identified 373,070 breakthrough infections with an incidence of 11.2 (95% ...
Development of vibrational spectroscopic methods combined with chemometrics for the detection and quantification of nicotine in e-liquids.
improvement of Raman PLS model and further SERS studies with tests on a larger number of samples are still needed. Health Topics: E-sigaret E-cigarette E-cigarette Service: Médicaments et produits de santé ...
Chemical and toxciological characterization of e-liquid cigarettes
quantitative in silico models. In total, potential genotoxicity activity was predicted for 44 flavourings. Based on information from European databases, genotoxicity could be confirmed for five of these ...
Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019.
Keywords: Biological Products Drug Development Human Experimentation Humans vaccines whole genome sequencing Abstract: Controlled human infection models can be helpful to study pathogenesis and immune ...
Identification of Flavouring Substances of Genotoxic Concern Present in E-Cigarette Refills
investigated in silico with two complementary (quantitative) structure-activity relationship ((Q) SAR) models (Derek Nexus, Sarah Nexus). In total, 57 flavouring components were identified with a structural ...