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Mycobacterium tuberculosis with disruption in genes encoding the phosphate binding proteins PstS1 and PstS2 is deficient in phosphate uptake and demonstrates reduced in vivo virulence.
Huygen, Kris; Content, Jean Source: Infect Immun, Volume 73, Issue 3, p.1898-902 (2005) Keywords: Animals Bacterial Proteins Culture Media Gene Deletion Humans mice Mice, Inbred BALB C Mice, Inbred C57BL ...
Induction of in vivo functional Db-restricted cytolytic T cell activity against a putative phosphate transport receptor of Mycobacterium tuberculosis.
Histocompatibility Antigen H-2D Interferon-gamma Interleukin-2 mice Mice, Inbred C57BL Molecular Sequence Data Mycobacterium tuberculosis T-Lymphocytes, Cytotoxic Th1 Cells Tuberculosis Vaccines Vaccines, DNA ...
Mapping of murine Th1 helper T-Cell epitopes of mycolyl transferases Ag85A, Ag85B, and Ag85C from Mycobacterium tuberculosis.
Immunization mice Mice, Inbred BALB C Mice, Inbred C57BL Molecular Sequence Data Mycobacterium tuberculosis Th1 Cells Tuberculosis Vaccines Tuberculosis, Pulmonary Vaccines, DNA Abstract: BALB /c (H-2(d)) and ...
Improved tuberculosis DNA vaccines by formulation in cationic lipids.
Bacterial ATP-Binding Cassette Transporters Bacterial Proteins BCG Vaccine Cations Injections, Intramuscular Interferon-gamma Interleukin-2 Lipids Lung mice Mice, Inbred BALB C Mice, Inbred C57BL ...
Culture filtrate specific H-2(b) restricted CD8+ T cells activated in vivo by Mycobacterium tuberculosis or bovis BCG recognize a restricted number of immunodominant peptides.
Mice, Inbred BALB C Mice, Inbred C57BL Mycobacterium bovis Mycobacterium tuberculosis Peptides Abstract: We previously demonstrated that Bacillus Calmette-Guerin (BCG) immunization activated D(b) ...
CD4+ T cells contain Mycobacterium tuberculosis infection in the absence of CD8+ T cells in mice vaccinated with DNA encoding Ag85A.
p.2455-9 (2000) Keywords: Animals Antigens, Bacterial BCG Vaccine beta 2-Microglobulin CD4-Positive T-Lymphocytes CD8-Positive T-Lymphocytes Interferon-gamma mice Mice, Inbred BALB C Mice, Inbred C57BL ...
Tuberculosis DNA vaccine encoding Ag85A is immunogenic and protective when administered by intramuscular needle injection but not by epidermal gene gun bombardment.
Interleukin-4 Lung mice Mice, Inbred BALB C Mice, Inbred C57BL Mycobacterium tuberculosis Spleen T-Lymphocytes, Cytotoxic Tuberculosis Vaccination Vaccines, DNA Abstract: Immunogenicity and protective efficacy of ...
Cloning of the gene encoding a 22-kilodalton cell surface antigen of Mycobacterium bovis BCG and analysis of its potential for DNA vaccination against tuberculosis.
p.1040-7 (2000) Keywords: Animals Antigens, Bacterial BCG Vaccine Cloning, Molecular Cytokines mice Mice, Inbred BALB C Mice, Inbred C57BL Molecular Weight Vaccines, DNA Abstract: Using spleen cells from ...
Characterization of the culture filtrate-specific cytotoxic T lymphocyte response induced by Bacillus Calmette-Guérin vaccination in H-2b mice.
CD8-Positive T-Lymphocytes Cell Line Chloroquine Culture Media H-2 Antigens Interferon-gamma Lymphocyte Activation Membrane Glycoproteins mice Mice, Inbred C57BL Perforin Pore Forming Cytotoxic Proteins ...
Immunogenicity and protective efficacy of tuberculosis DNA vaccines encoding putative phosphate transport receptors.
coli Proteins Female Interleukin-2 Lung mice Mice, Inbred C57BL Mycobacterium Mycobacterium tuberculosis Periplasmic Binding Proteins Phosphate-Binding Proteins Phosphates Plasmids Spleen Tuberculosis ...