Search results - 44 results

A healthy lifestyle is positively associated with mental health and well-being and core markers in ageing

using qPCR. Generalised linear mixed models were used while adjusting for a priori chosen covariates. RESULTS: The average age (SD) of the study population was 49.9 (17.5) years, and 48.8% were men. ...

Residential green space in association with the methylation status in a CpG site within the promoter region of the placental serotonin receptor HTR2A

these associations are already evident during foetal development. Similar biological signals shape the developmental processes in the foetal brain and placenta.Therefore, we hypothesize that green space ...

Identifying nanodescriptors to predict the toxicity of nanomaterials: a case study on titanium dioxide

outcome of computational modelling. In this study, we aim to identify nanodescriptor(s) and biological endpoint(s) capable of predicting the toxicity of titanium-di-oxide (TiO2) NM s, and demonstrate how ...

Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019.

Keywords: Biological Products Drug Development Human Experimentation Humans vaccines whole genome sequencing Abstract: Controlled human infection models can be helpful to study pathogenesis and immune ...

Modelling for Taenia solium control strategies beyond 2020

aimed at refining the post-2020 targets for control of T. solium for a new roadmap for neglected tropical diseases. In response, two groups working on taeniasis and cysticercosis mathematical models ...

Performance of in silico models for mutagenicity prediction of food contact materials

demonstrate that performance varies among the four models, but can be increased by applying a combination strategy. Furthermore, the importance of the applicability domain is illustrated. Limited performance to ...

MALT1 controls attenuated rabies virus by inducing early inflammation and T cell activation in the brain.

study the impact of MALT1 on virus infection in the brain, using the attenuated ERA rabies virus in different models of MALT1 deficient mice. We reveal the importance of MALT1-mediated inflammation and ...

Invasion by the Alien Tree Alters Ecosystem Functions in a Temperate Deciduous Forest

biogeochemical cycles biological invasion canopy foliar nutrients exotic species heterotrophic respiration invasive species litter Abstract: Alien invasive species can affect large areas, often with wide-ranging ...

Attenuation of RNA viruses by redirecting their evolution in sequence space.

Antibodies, Neutralizing Antibodies, Viral Codon Codon, Nonsense Coxsackievirus Infections Disease Models, Animal Dogs Enterovirus B, Human HEK293 Cells HeLa Cells Humans Influenza A Virus, H1N1 Subtype Madin ...

Mechanisms Linking Colorectal Cancer to the Consumption of (Processed) Red Meat: A Review.

Keywords: Animals Carcinogens Colorectal Neoplasms Diet Disease Models, Animal Food Handling Heterocyclic Compounds Humans Lipid Peroxidation Meat Products Polycyclic Aromatic Hydrocarbons Red Meat Risk ...

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