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Half-fraction and full factorial designs versus central composite design for retention modelling in reversed-phase ion-pair liquid chromatography
mobile phase pH is fixed at 5.0 for methanol as well as for acetonitrile as organic modifers. The full factorial design, applied with acetonitrile as organic modifer, enables the selection of suitable LC ...
Genetic modification through oligonucleotide-mediated mutagenesis. A GMO regulatory challenge?
Publication Type: Peer reviewed scientific article Authors: Didier Breyer; Philippe Herman; Brandenburger, Annick; Gheysen, Godelieve; Remaut, Erik; Soumillion, Patrice; Van Doorsselaere, Jan; Custers, René; Katia Pauwels; Myriam Sneyers; Reheul, Dirk Sou ...
Batch release of vaccines in Europe: from method transfer to first commercial batch available on the market. Straightforward approach that requires a proactive mindset of the manufacturer.
product specifications or on relevant batch record data (which are usually supplied in section 3 of the protocol). Important modifications of the manufacturing and testing procedures, changes in reagents ...
The Phage-Encoded-Acetyltransferase Rac Mediates Inactivation of Transcription by Cleavage of the RNA Polymerase Alpha Subunit.
disconnects the C-terminal domain, required for transcription initiation from most highly active cellular promoters. To achieve this, Rac likely taps into a novel post-translational modification (PTM) mechanism ...
Capturing respiratory syncytial virus season in Belgium using the influenza severe acute respiratory infection surveillance network, season 2018/19.
and complications.ConclusionWith only marginal modifications in the case definition and the period of surveillance, the Belgian SARI network would be able to substantially contribute to RSV surveillance ...
Objective understanding of the Nutri-score front-of-pack label by European consumers and its effect on food choices: an online experimental study.
modifications were smaller, but the effect of the Nutri-Score seemed slightly higher in eliciting healthier food choices overall compared with the Reference Intakes, followed by the Warning symbols, the Multiple ...
Identification of an unauthorized genetically modified bacteria in food enzyme through whole-genome sequencing.
characterize the genetic modification comprising a sequence from the pUB110 shuttle vector (GenBank: M19465.1), harbouring antimicrobial resistance genes conferring a resistance to kanamycine, neomycin and ...