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In silico methods for chromosome damage

although they are in general less developed than those for mutagenicity, in silic o tools for chromosome damage can provide valuable information, especially when combined in a battery. Health Topics:  Food ...

Identification of flavouring substances of genotoxic concern present in e-cigarette refills

Rogiers, Vera; Deconinck, Eric; Vanhaecke, Tamara Source: Food and Chemical Toxicology, Volume 147, Issue 111864 (2021) Keywords: (Q)SAR methodologies e-cigarettes genotoxicity mutagenicity Abstract: ...

Comments on the “Evaluation of the Genotoxicity of Cell Phone Radiofrequency Radiation in Male and Female Rats and Mice Following Subchronic Exposure” by Smith‐Roe et al.

female rats and mice following subchronic exposure. Smith-Roe SL, Wyde ME, Stout MD, Winters JW, Hobbs CA, Shepard KG, Green AS, Kissling GE, Shockley KR, Tice RR, Bucher JR, Witt KL.Environ Mol Mutagen ...

In Vitro and In Vivo Toxicity Studies on Cymbopogon giganteus Chiov. Leaves Essential Oil from Benin

African countries. The present study aims to evaluate the oral and inhalation toxicity as well as the mutagenic effects of the essential oil of Cymbopogon giganteus leaves (EOCG) from a sample collected in ...

Assessing the receptor-mediated activity of PAHs using AhR-, ERα- and PPARγ- CALUX bioassays

been reported to have carcinogenic and/or mutagenic properties, another possible negative health impact is their endocrine disrupting potential. Therefore, the aim of this study was to determine both the ...

In vitro 50 Hz magnetic field long-term exposure: Cytogenetic tests on human lymphoblastoid TK6 cells and validation of the test environment

effects of long-term exposure to ELF-(E) MF s on the genetic material and the impact of long-term pre-exposure to ELF-(E) MF s on the sensitivity of cells to the damage induced by known mutagens are needed. ...

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

Sigrid; Rogiers, Vera; Doktorova, Tatyana Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...

Performance of in silico models for mutagenicity prediction of food contact materials

Toxicological Sciences, Volume 163, Issue 2 (2018) Keywords: (Q)SAR food contact materials In silico mutagenicity VALIDATION Abstract: In silico methodologies, such as (quantitative) structure-activity ...

Coatings in food contact materials: Potential source of genotoxic contaminants?

Toxicol, Volume 106, Issue Pt A, Number 505, p.496-505 (2017) Keywords: Consumer Product Safety Food Contamination Food Packaging Humans Mutagenicity Tests Mutagens Abstract: Up till now, no harmonized EU ...

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