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In Silico Methods for Chromosome Damage.
Keywords: Chromosome Aberrations Chromosomes DNA Damage Humans Mutagenicity Tests Mutagens Mutation Abstract: Due to the link with serious adverse health effects, genotoxicity is an important toxicological ...
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
Keersmaecker; Rogiers, Vera; Tatyana Y. Doktorova Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...
Isolation and characterization of the compounds responsible for the antimutagenic activity of Combretum microphyllum (Combretaceae) leaf extracts
inhibit the pathological process resulting from exposure to mutagens. Investigation of the antimutagenic potential of traditional medicinal plants and compounds isolated from plant extracts provides one of ...
Slurry photocatalytic membrane reactor technology for removal of pharmaceutical compounds from wastewater: Towards cytostatic drug elimination
compounds and their metabolites, as well as their degraded by-products have genotoxic and mutagenic effects. A major challenge of cytostatic removal stands in the fact that most drugs are delivered to ...
In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.
Alessandra; Milushev, Dimiter; Benfenati, Emilio; Rogiers, Vera; Doktorova, Tatyana Y Source: Mutagenesis, Volume 31, Number 461, p.453-61 (2016) Keywords: Cosmetics In silico Mutagenicity Tests Transcriptomics ...
In vitro mutagenicity and antimutagenicity of dichloromethane leaf extracts of seven Protea species using Ames test
Publication Type: Peer reviewed scientific article Authors: Makgapeetja, M.D.; Makhafola, T.J.; Pieters, L.; Luc Verschaeve; Elgorashi, E.E. Source: South African Journal of Botany, Volume 103, Number 326 (2016) Keywords: aflatoxin B1 Ames test Neutral Re ...
Genotoxicity and Antigenotoxicity Studies of Traditional Medicinal Plants: How Informative and Accurate are the Results?
Mutagens Phytotherapy Plant Extracts Plants, Medicinal Abstract: Genotoxicity and antigenotoxicity studies of (traditional medicinal) plants are important from a risk assessment point of view and in the ...
Testing chemical agents with the cytokinesis-block micronucleus cytome assay.
Humans Micronuclei, Chromosome-Defective Micronucleus Tests Mutagens Abstract: In order to evaluate the applicability of the cytokinesis-block micronucleus cytome assay in routine mutagenicity testing we ...
Mutagenicity, antimutagenicity and cytotoxicity evaluation of South African Podocarpus species
Keywords: Antimutagenicity cytotoxicity mutagenicity Podocarpus Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Four species of Podocarpus are used in traditional medicine both in human and animal healthcare in ...
Toxic and mutagenic properties of extracts from Tunisian traditional medicinal plants investigated by the neutral red uptake, VITOTOX and alkaline comet assays
Publication Type: Peer reviewed scientific article Authors: Edziri, H.; Mastouri, M.; Mahjoub, A.; R. Anthonissen; Birgit Mertens; Cammaerts, S.; Gevaert, L.; Luc Verschaeve Source: South African Journal of Botany, Volume 77, Issue 3, Number 710 (2011) Ke ...