Search results - 31 results

Recurrent tuberculosis in a young child

A young child, 19 months of age, presented with a second episode of tuberculosis after full recovery from initial tuberculosis disease 6 months earlier. Mycobacterium tuberculosis strains isolated from both ...

Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.

Volume 4 (2019) Abstract: Two billion people are infected with, leading to 10 million new cases of active tuberculosis and 1.5 million deaths annually. Universal access to drug susceptibility testing (DST) ...

In vitro activity of bedaquiline against slow-growing nontuberculous mycobacteria.

J Med Microbiol (2019) Keywords: Bedaquiline Mycobacteria nontuberculous Abstract: Bedaquiline (BDQ) is a recently approved antibiotic for the treatment of multidrug-resistant tuberculosis, but its ...

Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid

Source: Tuberculosis, Volume 117 (2019) Keywords: Delamanid Mycobacterium tuberculosis RNA sequencing Transciptomics Abstract: Tuberculosis (TB) is the most deadly infectious disease worldwide. To reduce TB ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

microbes and vectors, Issue Institute Pasteur, Paris, France (2018) Keywords: Mycobacterium tuberculosis; antimicrobial resistance; diagnostics Abstract: To counter the long turnaround time of standard ...

Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing

recommends drug-susceptibility testing of Mycobacterium tuberculosis complex for all patients with tuberculosis to guide treatment decisions and improve outcomes. Whether DNA sequencing can be used to ...

Allergic Asthma Favors Growth in the Lungs of Infected Mice.

allergic asthma Brucella melitensis Brucellosis INFECTION Mycobacterium tuberculosis Streptococcus pneumoniae Abstract: Allergic asthma is a chronic Th2 inflammatory disease of the lower airways affecting ...

A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.

profiles; phenotypic resistance to isoniazid, rifampicin, ethambutol, pyrazinamide, and capreomycin; and corresponding drug resistance mutations. We whole-genome sequenced all Mycobacterium tuberculosis ...

Meropenem-clavulanate for drug-resistant tuberculosis: a follow-up of relapse-free cases.

Volume 22, Issue 1 (2018) Keywords: Carbapenems repurposed drugs XDR-TB Abstract: BACKGROUND: Extensively drug-resistant tuberculosis (XDR- TB), defined as TB caused by a Mycobacterium strain resistant to ...

Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection

Mycobacterium avium subsp. hominissuis (Mah) represents a health concern for humans and to a lesser extent for pigs, but its zoonotic potential remains elusive. Using multispacer sequence typing (MST) we ...

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