Search results - 48 results

Synthesis and anti-tubercular activity of N(2)-arylbenzo[g]isoquinoline-5,10-dione-3-iminium bromides.

Sensitivity Tests Molecular Conformation Mycobacterium tuberculosis Structure-Activity Relationship Tuberculosis, Multidrug-Resistant Abstract: Tuberculosis has remained a challenge for medicinal chemists ...

Evaluation of the Speed-Oligo Mycobacteria assay for the identification of nontuberculous mycobacteria.

Mycobacterium tuberculosis complex, and one M. chelonae strain and one M. peregrinum strain were both identified as Mycobacterium abscessus. Moreover, one M. chelonae strain was not identified by Speed-Oligo ...

Safety, immunogenicity, and efficacy of the candidate tuberculosis vaccine MVA85A in healthy adults infected with HIV-1: a randomised, placebo-controlled, phase 2 trial.

Mycobacterium tuberculosis infection and disease, assessed in the per-protocol population. Immunogenicity was assessed in a subset of participants at day 7 and day 28 after the first and second vaccination, and ...

False-positive rifampicin resistance on Xpert® MTB/RIF caused by a silent mutation in the rpoB gene.

Isoniazid Male Molecular Sequence Data Mutation Mycobacterium tuberculosis Phenotype Pyrazinamide Rifampin Sensitivity and Specificity sputum Tuberculosis, Pulmonary Abstract: The Xpert® MTB / RIF assay ...

Anti-mycobacterial activity of 1,3-diaryltriazenes.

spread of the drug resistant tuberculosis has led to an ongoing demand for novel compounds for therapeutic use. Identification and study of compounds with the ability to inhibit Mycobacterium tuberculosis ...

Biological evaluation of diazene derivatives as anti-tubercular compounds.

research in the past and present, Mycobacterium tuberculosis (M.tb), the etiological agent of tuberculosis, still causes more than a million deadly casualties each year, second only to HIV. The rapid ...

From multidrug- to extensively drug-resistant tuberculosis: upward trends as seen from a 15-year nationwide study.

Male Mutation Mycobacterium tuberculosis REGISTRIES Treatment Outcome Tuberculosis, Multidrug-Resistant Young adult Abstract: BACKGROUND: Emergence of extensively drug-resistant tuberculosis (XDR- TB) ...

M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.

Mutation Mycobacterium bovis Mycobacterium tuberculosis Mycolic Acids Organ Specificity Oxygen Species Specificity Spleen Th1 Cells Th17 Cells Trachea Treatment Outcome Tuberculosis Vaccination virulence ...

Biological evaluation of bisbenzaldehydes against four Mycobacterium species.

avium Mycobacterium bovis Mycobacterium tuberculosis Mycobacterium ulcerans Species Specificity Abstract: A series of bisbenzaldehydes and structurally related analogs, conveniently synthesized via ...

Systematic analysis of pyrazinamide-resistant spontaneous mutants and clinical isolates of Mycobacterium tuberculosis.

Issue 10, p.5186-93 (2012) Keywords: Amidohydrolases Antitubercular Agents Crystallography, X-Ray Microbial Sensitivity Tests Mutation Mycobacterium tuberculosis Pyrazinamide Abstract: Pyrazinamide (PZA) ...

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