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Search results - 17 results

A Refined Guinea Pig Model of Foot-and-Mouth Disease Virus Infection for Assessing the Efficacy of Antiviral Compounds.

Publication Type: Peer reviewed scientific article Authors: Annebel De Vleeschauwer; David Lefebvre; Willems, T; Paul, G; Billiet, A; Murao, L E; Neyts, J; Goris, N; Kris De Clercq Source: ...

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.

Cameron, Craig E; Verdaguer, Nuria; Neyts, Johan; van Kuppeveld, Frank J M Source: PLoS Pathog, Volume 11, Issue 3, p.e1004733 (2015) Keywords: Animals Antiviral Agents Binding Sites Cardiovirus ...

A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus.

King, Donald P; Neyts, Johan; Kris De Clercq Source: Biochem Biophys Res Commun, Volume 455, Issue 3-4, p.378-81 (2014) Keywords: Animals Antiviral Agents Benzimidazoles Cell Line Cell Survival ...

Proof of concept for the inhibition of foot-and-mouth disease virus replication by the anti-viral drug 2'-C-methylcytidine in severe combined immunodeficient mice.

Publication Type: Peer reviewed scientific article Authors: David Lefebvre; Annebel De Vleeschauwer; Goris, N; Kollanur, D; Billiet, A; Murao, L; Neyts, J; Kris De Clercq Source: Transbound Emerg ...

In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.

Publication Type: Peer reviewed scientific article Authors: Osiceanu, Ana-Maria; Murao, Lyre Espada; Kollanur, Denny; Swinnen, Jan; Annebel De Vleeschauwer; David Lefebvre; Kris De Clercq; Neyts, ...

Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.

Lefebvre, David; Lanke, Kjerstin H W; Kris De Clercq; Hilgenfeld, Rolf; Neyts, Johan; van Kuppeveld, Frank J M Source: Antiviral Res, Volume 103, p.17-24 (2014) Keywords: Animals Antiviral Agents Cell Line ...

Intra-host variation structure of classical swine fever virus NS5B in relation to antiviral therapy.

Publication Type: Peer reviewed scientific article Authors: Andy Haegeman; Vrancken, Robert; Neyts, Johan; F. Koenen Source: Antiviral Res, Volume 98, Issue 2, p.266-72 (2013) Keywords: Amino Acid ...

Diagnostic performance and application of two commercial cell viability assays in foot-and-mouth disease research.

Publication Type: Peer reviewed scientific article Authors: Willems, Tom; David Lefebvre; Neyts, Johan; Kris De Clercq Source: J Virol Methods, Volume 173, Issue 1, p.108-14 (2011) Keywords: Animals ...

Development of a foot-and-mouth disease infection model in severe combined immunodeficient mice for the preliminary evaluation of antiviral drugs.

Publication Type: Peer reviewed scientific article Authors: David Lefebvre; Neyts, J; Kris De Clercq Source: Transbound Emerg Dis, Volume 57, Issue 6, p.430-3 (2010) Keywords: Animals Antiviral ...

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