Search results - 27 results
Substandard and falsified ivermectin tablets obtained for self-medication during the COVID-19 pandemic as a source of potential harm.
self-administration of substandard or falsified (SF) medicines bearing harmful quality deficiencies have contributed to this phenomenon. In order to have a better view on the nature of these harmful quality ...
Microbial quality analysis of falsified medicines seized by controling agencies
medications are mainly encountered in developing region, the criminal focus in western countries seems to center more on lifestyle medicines, including sexual performance enhancers, sport performance boosters, ...
Multidimensional chromatographic fingerprinting combined with chemometrics for the identification of regulated plants in suspicious plant food supplements
order to tackle this problem, a feasibility study based on a combination of chemometrics and multidimensional fingerprints recorded using chromatography was carried out. Chromatographic fingerprints ...
COMBINATION OF CHEMOMETRICS AND MULTIDIMENSIONAL FINGERPRINTING FOR DETECTION OF REGULATED PLANTS IN PLANT FOOD SUPPLEMENTS
fingerprints by performing a correlation analysis on the DAD data. Chemometric analysis was carried out using two approaches: 1. binary models for each plant separately and 2. multiclass models. The data were ...
Clustering of Tadalafil API Samples According to their Manufacturer in the Context of API Falsification Detection
Official Medicines Control Laboratory Network (GEON), on tadalafil. A classical market surveillance study, evaluating compliance to the European Pharmacopoeia, was combined with a fingerprint study, the ...
From b to y ions, a decade of experience with peptide and protein analysis
elaborate on the techniques we employ to analyze such samples and give an overview of the substances we’ve encountered during the last decade. Health Topics: Médicaments illégaux Illegal medicines Illegale ...
CHROMATOGRAPHIC FINGERPRINT DEVELOPMENT FOR THE DETECTION OF TRIBULUS TERRESTRIS IN PLANT FOOD SUPPLEMENTS
spectrometry Results and conclusion: It was found and confirmed that 7 unknown samples showed the pres-ence of TT and more than half of it were confirmed for adulteration, i.e. adding TT without indication on ...
chromatographic fingerprinting for the detection of herbal adulteration and herbal fraud in plant food supplements
not contain the plant or herb declared on the packaging. This can be either due to falsification or fraud, or confounding. (b) adulteration, with the distinction between chemical adulteration and herbal ...
Relative response factors and multiple regression models in liquid chromatography to quantify low-dosed components using alternative standards-proof of concept: total Δ9-THC content in cannabis flowers using CBD as reference.
was used as a case study. A chromatographic method was implemented and validated, and the use of classical calibration lines, classical RRF, and the LRRFM was applied and compared, with special focus on ...
OMCL testing and the API working group: Part of the solution?
a fingerprint study (MSSFP). An MSS, according to Ph. Eur. only gives an indication of the quality of the product on some distinct parameters, often chosen based on the manufacturing process. A MSSFP study allows ...