- Did you mean
- lentivirus
Search results - 21 results
Proof of concept for the reduction of classical swine fever infection in pigs by a novel viral polymerase inhibitor.
potent in vitro antiviral activity against pestiviruses including classical swine fever virus (CSFV). This study analysed whether the lead compound, BPIP, was able to reduce virus replication in infected ...
A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase.
binding site as BPIP or VP32947 at the top of the finger domain of the polymerase that is a “hot spot” for inhibition of pestivirus replication. Health Topics: Animal health Category: A1 FOS ...
Imidazo[4,5-c]pyridines inhibit the in vitro replication of the classical swine fever virus and target the viral polymerase.
[3-[((2-dipropylamino)ethyl)thio]-5H-1,2,4-triazino [5,6-b]indole], an unrelated earlier reported selective inhibitor of pestivirus replication. BPIP-resistant CSFV carried a T259S mutation in NS5B, encoding the RNA-dependent RNA-polymerase (RdRp). ...
Validation of two commercial real-time RT-PCR kits for rapid and specific diagnosis of classical swine fever virus.
“pestivirus specificity”, reproducibility and ease of handling, using 189 different samples. These samples were either CSFV inactivated strains or blood/serum/organs collected from CSFV experimentally infected ...
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
J Virol, Volume 81, Issue 20, p.11046-53 (2007) Keywords: Animals Antiviral Agents Binding Sites Cattle Diarrhea Viruses, Bovine Viral Enzyme Inhibitors Models, Molecular Pestivirus Pestivirus Infections ...
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.
Johan Source: J Virol, Volume 80, Issue 1, p.149-60 (2006) Keywords: Antiviral Agents Diarrhea Virus 1, Bovine Viral Drug Resistance, Viral Imidazoles Lethal Dose 50 Mutation Pestivirus Pyridines RNA ...
Diversity among bovine pestiviruses.
Publication Type: Peer reviewed scientific article Authors: Hamers, C; Dehan, P; Couvreur, B; Letellier, C; Pierre Kerkhofs; Pastoret, P P Source: Vet J, Volume 161, Issue 2, p.112-22 (2001) Keywords: Animals Antibodies, Monoclonal Antigenic Variation Bov ...
Classical swine fever virus: a second ring test to evaluate RT-PCR detection methods.
One set comprised 25 samples of random primed cDNA, synthesised from viral RNA representative of different pestiviruses. The other set comprised samples of blood and serum obtained from virus-free or ...
Detection and genotyping of bovine diarrhea virus by reverse transcription-polymerase chain amplification of the 5' untranslated region.
bovine diarrhea virus (BVDV) from other pestiviruses, and to determine the genotype of the BVDV isolates. For this purpose, primer pairs were selected in the 5’ untranslated region (5’ UTR). The primers BE ...
Polymerase chain reaction-mediated cloning and in vitro translation of the genes coding for the structural proteins of hog cholera virus.
Keywords: Base Sequence Classical swine fever virus Cloning, Molecular Molecular Sequence Data Pestivirus polymerase chain reaction Protein Biosynthesis Viral Structural Proteins Abstract: After amplification ...