Search results - 5 results

Optimization of Long-Acting Bronchodilator Dose Ratios Using Isolated Guinea Pig Tracheal Rings for Synergistic Combination Therapy in Asthma and COPD.

tiotropium bromide monohydrate (TIO) to assess their synergistic potential. This was done using an appropriate ex vivo model of isolated perfused guinea pig tracheal rings, and pharmacological models of drug ...

Assessment of information as regards the toxicity of fumonisins for pigs, poultry and horses

fumonisins Horses Pigs Poultry toxicity Abstract: In 2018, the EFSA Panel on Contaminants in the Food Chain (CONTAM) adopted a Scientific Opinion on the risks for animal health related to the presence of ...

Risk assessment of nitrate and nitrite in feed

of 2.0 mg nitrate/kg bw per day in pigs’ feeds indicate a low risk for adverse health effects, when compared with an identified no observed adverse effect level (NOAEL) of 410 mg nitrate/kg bw per day, ...

Risk assessment of ochratoxin A in food

exposure (MOE) approach was applied. For the characterisation of non‐neoplastic effects, a BMDL10  of 4.73 μg/kg body weight (bw) per day was calculated from kidney lesions observed in pigs. For ...

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