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Using a combination of short- and long-read sequencing to investigate the diversity in plasmid- and chromosomally encoded extended-spectrum beta-lactamases (ESBLs) in clinical Shigella and Salmonella isolates in Belgium
Publication Type: Peer reviewed scientific article Authors: Berbers, Bas; Vanneste, Kevin; Roosens, Nancy H. C. J.; Marchal, Kathleen; Pieter-Jan Ceyssens *; De Keersmaecker, Sigrid C. J. Source: Microbial Genomics, Volume 9, Issue 1 (2023) Health Topics: ...
A genomic appraisal of invasive Salmonella Typhimurium and associated antibiotic resistance in sub-Saharan Africa.
ST313- L2 likely emerged in the Democratic Republic of Congo around 1980 and further spread in the mid 1990s. We observed plasmid-borne as well as chromosomally encoded fluoroquinolone resistance ...
A global genomic analysis of Salmonella Concord reveals lineages with high antimicrobial resistance in Ethiopia.
demonstrate the presence of AMR markers integrated in structurally diverse IncHI2 and IncA/ C2 plasmids, and/or the chromosome. Molecular surveillance of pathogens such as S. Concord supports the understanding ...
First Belgian Report of Ertapenem Resistance in an ST11 Klebsiella Pneumoniae Strain Isolated from a Dog Carrying blaSCO-1 and blaDHA-1 Combined with Permeability Defects
ertapenem, third-generation cephalosporins and fluoroquinolones. A hybrid approach, combining long- and short-read sequencing, was employed for in silico plasmid characterization, multi-locus sequence typing ...
Genomic epidemiology of persistently circulating MDR Shigella sonnei strains associated with men who have sex with men (MSM) in Belgium (2013–19)
various incompatibility (Inc)-type plasmids, the SpA plasmid and ESBL genes. CONCLUSIONS: In Belgium, S. sonnei isolates from men are much more likely to be resistant to important first-line antibiotics ...
First detection of a plasmid-encoded New-Delhi metallo-beta-lactamase-1 (NDM-1) producing Acinetobacter baumannii using whole genome sequencing, isolated in a clinical setting in Benin.
beta-Lactamases Female Humans Plasmids whole genome sequencing Abstract: BACKGROUND: Carbapenem-resistant Acinetobacter baumannii is considered a top priority pathogen by the World Health Organization for ...
Public microbial resources centres: key hubs for FAIR microorganisms and genetic materials.
microbiology, microbial domain biological resource centres (mBRCs) have a long-standing experience in preserving and distributing authenticated microbial strains and genetic materials (e.g., recombinant plasmids ...
Great diversity in Mcr-1 encoding plasmids among human E. coli and Salmonella spp. isolates in Belgium
Publication Type: Scientific poster, presentation or proceeding Authors: Pieter-Jan Ceyssens; Bogaerts, Pierre; Sigrid C.J. De Keersmaecker; Sophie Bertrand; Glupzynski, Youri Source: ECCMID 2017, ESCMID, Volume 1, Issue ESCMID, Vienna, Austria (2017) Key ...
Whole Genome Sequence Analysis of Salmonella Enteritidis PT4 Outbreaks from a National Reference Laboratory's Viewpoint.
a non-common source of contamination. Also, an additional plasmid carrying an antibiotic resistance gene was discovered in the human isolate with the variant phage type PT4 a. DISCUSSION: For the two ...
A multifaceted study of Pseudomonas aeruginosa shutdown by virulent podovirus LUZ19
completely inhibit P. aeruginosa growth when expressed from a single-copy plasmid. Since Gp13 encodes a predicted GNAT acetyltransferase, this observation points at a crucial but yet unexplored level of ...