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Streptococcus pyogenes infections with limited emm-type diversity in the homeless population of Brussels, 2016-2018.

Bossuyt; Anne Botteaux; Pierre R Smeesters Source: Int J Infect Dis, Volume 81 (2019) Keywords: Adult Bacterial Outer Membrane Proteins Belgium Cluster Analysis Female Homeless Persons Humans Male middle ...

Paediatric haemolytic uraemic syndrome related to Shiga toxin-producing, an overview of 10 years of surveillance in France, 2007 to 2016.

Hospitalier de Surveillance du Shu Pédiatrique Source: Euro Surveill, Volume 24, Issue 8 (2019) Keywords: Child Disease Outbreaks Escherichia coli Infections Escherichia coli Proteins Feces France ...

Falsification of biotechnology drugs: current dangers and/or future disasters?

falsified medical products in the developed world. In recent years, also biotechnology drugs (synthetic peptide drugs and protein drugs) have been reported to be prone for falsifications. Next to the ...

Estimating the Reliability of Low-Abundant Signals and Limited Replicate Measurements through MS2 Peak Area in SWATH

Keywords: MS2 peak area Abstract: Sequential windows acquisition of all theoretical fragment ions mass spectrometry (SWATH- MS) provides large-scale protein quantification with high accuracy and selectivity. ...

Differences in antigenic sites and other functional regions between genotype A and G mumps virus surface proteins.

Koopmans; Rob van Binnendijk; Elien Vandermarliere Source: Sci Rep, Volume 8, Issue 1 (2018) Keywords: Mumps; vaccine Abstract: The surface proteins of the mumps virus, the fusion protein (F) and ...

Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.

incomplete understanding of the pathogenesis. MALT1 mediates activation of several immune cell types and is involved in the proliferation and survival of cancer cells. MALT1 acts as a scaffold protein for ...

Y-box-binding protein 1 supports the early and late steps of HIV replication.

König; Gijsbers, Rik; De Rijck, Jan; Debyser, Zeger Source: PLoS One, Volume 13, Issue 7 (2018) Abstract: The human immunodeficiency virus (HIV) depends on cellular proteins, so-called cofactors, to ...

MALT1 controls attenuated rabies virus by inducing early inflammation and T cell activation in the brain.

acts as a scaffold protein for NF-κB signalling and a cysteine protease that cleaves substrates, further promoting the expression of immunoregulatory genes. Deregulated MALT1 activity has been associated ...

Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans

polymerase Abstract: The optimized exploitation of cell resources is one cornerstone of a successful infection. Differential mapping of host-pathogen protein-protein interactions (PPI s) on the basis of ...

Molecular surveillance of Plasmodium falciparum resistance to artemisinin-based combination therapies in the Democratic Republic of Congo.

Combination Gene Dosage Genetic Markers Geography Haplotypes Humans Malaria, Falciparum Mutation Plasmodium falciparum Polymorphism, Genetic Protozoan Proteins Abstract: Malaria is a major public health problem ...

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