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Combined deficient response to polysaccharide-based and protein-based vaccines predicts a severe clinical phenotype

Publication Type: Peer reviewed scientific article Authors: Cockx, Maaike; Haerynck, Filomeen; Hoste, Levi; Schrijvers, Rik; Van der Werff ten Bosch, Jutte; Dillaerts, Doreen; Thomas, Debby; Schaballie, Heidi; Bucciol, Giorgia; Robberechts, Wiert; Patel, ...

ELM-the Eukaryotic Linear Motif resource-2024 update.

structural and functional components of modular eukaryotic proteins. They are also the most abundant, especially when considering post-translational modifications. As well as being found throughout the cell as ...

The phage-encoded PIT4 protein affects multiple two-component systems of Pseudomonas aeruginosa

urgently needed to develop alternative therapies. One path explored in this article is the use of bacteriophages and, more specifically, phage-derived proteins. In this study, a phage-derived protein was ...

Minimum information guidelines for experiments structurally characterizing intrinsically disordered protein regions.

Pritisanac, Iva; Tenorio, Luiggi; Viennet, Thibault; Tompa, Peter; Vranken, Wim; Tosatto, Silvio C E; Davey, Norman E Source: Nat Methods, Volume 20, Issue 9 (2023) Keywords: Intrinsically Disordered Proteins ...

Applicability of the DPRA on mixture testing: challenges and opportunities.

Keywords: Animal Testing Alternatives Animals Peptides Abstract: The in chemico direct peptide reactivity assay (DPRA) is validated to assess protein reactivity of chemical compounds, relating to the ...

Development of a Droplet Digital PCR to Monitor SARS-CoV-2 Omicron Variant BA.2 in Wastewater Samples

RT-ddPCR method that targets the T19I amino acid mutation in the spike protein of the SARS-CoV-2 genomes, which is specific to the BA.2 variant (omicron). The T19I assay was evaluated both in silico and in ...

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