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Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.

Agents Cell Line Cysteine Endopeptidases Drug Evaluation, Preclinical Genes, Reporter Humans Luciferases, Firefly Picornaviridae Protease Inhibitors Viral Proteins Abstract: Proteolytical cleavage of the ...

Antibacterial activity of a lectin-like Burkholderia cenocepacia protein.

Volume 2, Issue 4, p.566-75 (2013) Keywords: Bacterial Proteins Bacteriocins burkholderia Burkholderia Infections Humans Lectins Microbial Sensitivity Tests Abstract: Bacteriocins of the LlpA family have ...

Validation of a commercially available indirect ELISA using a nucleocapside recombinant protein for detection of Schmallenberg virus antibodies.

Nucleocapsid Proteins Orthobunyavirus Reagent Kits, Diagnostic Recombinant Proteins Reproducibility of Results Roc Curve Sheep Abstract: A newly developed Enzym Like Immuno Sorbant Assay (ELISA) based on the ...

Proteomic characterization of murid herpesvirus 4 extracellular virions.

Gillet, Laurent Source: PLoS One, Volume 8, Issue 12, p.e83842 (2013) Keywords: Animals Capsid Cell Line Cricetinae Extracellular Space Glycosylation Mass Spectrometry Proteomics Rhadinovirus Viral Proteins ...

M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.

Bert; Grooten, Johan; Fiers, Walter; Saelens, Xavier Source: PLoS One, Volume 8, Issue 3, p.e59081 (2013) Keywords: Adaptive Immunity Adaptor Proteins, Vesicular Transport Animals Female Humans Immunity, ...

An essential role for γ-herpesvirus latency-associated nuclear antigen homolog in an acute lymphoproliferative disease of cattle.

This hypothesis was further supported by the high frequencies of infected CD8 (+) T cells during MCF using immunodetection of ORF73 protein and single-cell RT- PCR approaches. Finally, the role of ...

Intra-host variation structure of classical swine fever virus NS5B in relation to antiviral therapy.

Substitution Animals Antiviral Agents Classical Swine Fever Classical swine fever virus Enzyme Inhibitors Genetic Variation Imidazoles Pyridines RNA Replicase Swine Viral Proteins Abstract: Classical swine fever ...

CP7_E2alf oral vaccination confers partial protection against early classical swine fever virus challenge and interferes with pathogeny-related cytokine responses.

revealed that both vaccinations attenuated the effects induced by CSFV on production of the pig major acute phase protein (PigMAP), IFN-α, IL-12, IL-10, and TGF-β1 cytokines. By this interference, several ...

Evaluation of classical swine fever virus antibody detection assays with an emphasis on the differentiation of infected from vaccinated animals.

HerdChek* CSFV Ab, both of which detect antibodies against the E2 protein of classical swine fever virus (CSFV), had the highest sensitivity. Both tests were practicable and showed good reproducibility. ...

Assessment of the long-term effect of vaccination on transmission of infectious bovine rhinotracheitis virus in cattle herds hyperimmunized with glycoprotein E-deleted marker vaccine.

Vaccines, Inactivated Viral Proteins Viral Vaccines Abstract: OBJECTIVE: To assess long-term effects and risk factors for the efficacy of hyperimmunization protocols against infectious bovine rhinotracheitis ...

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