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Phylogeography of Human and Animal Coxiella burnetii Strains: Genetic Fingerprinting of Q Fever in Belgium

Variable-number Tandem Repeat Analysis (MLVA) (n=146), Single-Nucleotide Polymorphism (SNP) (n=92) and Whole Genome Sequencing (WGS) (n=4) methods were used to characterize samples/strains during 2009-2019. Three ...

Phylogeography of Human and Animal Coxiella burnetii Strains: Genetic Fingerprinting of Q Fever in Belgium

Variable-number Tandem Repeat Analysis (MLVA) (n=146), Single-Nucleotide Polymorphism (SNP) (n=92) and Whole Genome Sequencing (WGS) (n=4) methods were used to characterize samples/strains during 2009-2019. Three ...

Precision cancer medicine: What has translated into clinical use in Belgium?

Semin Cancer Biol (2021) Keywords: cancer EVALUATION implementation Precision Medicine Abstract: RATIONALE: In 2016, Belgium launched the Next Generation Sequencing (NGS) Roadbook, consisting in 10 ...

A molecular assay for rapidly distinguishing the AviPro SALMONELLA VAC T vaccine strain from wild-type field isolates

resistance testing, but this sometime leads to ambiguous results with major economic implications. In this study, we used whole-genome sequencing to identify conserved and specific mutations in resistance and virulence ...

A bioinformatics WGS workflow for clinical complex isolate analysis, validated using a reference collection extensively characterized with conventional methods and approaches.

Keersmaecker; Nancy Roosens; Marchal, Kathleen; Vanessa Mathys; Vanneste, Kevin Source: J Clin Microbiol (2021) Abstract: The use of whole genome sequencing (WGS) for routine typing of bacterial isolates has ...

Whole-genome sequencing for TB source investigations: principles of ethical precision public health.

González-Candelas, F; Forier, A; Juengst, E Source: Int J Tuberc Lung Dis, Volume 25, Issue 3 (2021) Abstract: Whole-genome sequencing (WGS) of allows rapid, accurate inferences about the sources, location and timing ...

Outbreak of Central American born Shigella sonnei in two youth camps in Belgium in the summer of 2019

European Journal of Clinical Microbiology & Infectious Diseases (2021) Keywords: Cluster analyses Next-generation sequencing outbreak Shigella sonnei Abstract: In 2019, an outbreak of Shigella sonnei ...

Deepening of In Silico Evaluation of SARS-CoV-2 Detection RT-qPCR Assays in the Context of New Variants

COVID-19 diagnosis is the detection of viral RNA by RT-qPCR with a specific set of primers and probe. It is important to frequently evaluate the performance of these tests and this can be done first by an in ...

Staphylococcal enterotoxin gene cluster: prediction of enterotoxin (SEG and SEI) production and of the source of food poisoning based on Saβ typing.

Graber, H U Source: Appl Environ Microbiol (2020) Keywords: S. aureus SEG SEI vSaβ type whole genomic sequencing Abstract: Currently only five (SEA- SEE) out of 27 known staphylococcal enterotoxins can be ...

Genomic epidemiology of emerging ESBL-producing Kentucky in Europe.

present urinary-tract infections. Bayesian time-scaled phylogeny on whole genome sequences of isolates from these cases and supplementary isolates from public sequence databases was used to infer the origin ...

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