Search results - 81 results

Comprehensive toxicokinetic analysis reveals major interspecies differences in absorption, distribution and elimination of citrinin in pigs and broiler chickens

L/kg after IV administration). However, plasma protein binding did not differ statistically significant (91-98%). It is imperative to further investigate biotransformation and elimination pathways in ...

DETERMINATION OF SENSITIZING AND IRRITATING LEACHABLES IN MENSTRUAL HYGIENE PRODUCTS

putting the consumer at risk of sensi-tization. To assess the leaching of these chemicals, firstly a menstrual fluid simulant (MFS) that emulates pH, osmolarity and protein binding was developed. This MFS ...

Y-box-binding protein 1 supports the early and late steps of HIV replication.

to complete its replication cycle. In search for new therapeutic targets we identified the DNA and RNA binding protein Y-box-binding Protein 1 (YB-1) as a cofactor supporting early and late steps of ...

The role of methylation, DNA polymorphisms and microRNAs on HLA-G expression in human embryonic stem cells.

and protein are present or absent in hESC. Several lines of evidence indicate that promoter CpG methylation and 3’ untranslated region (3’ UTR) polymorphisms may influence HLA-G expression. We ...

DLL4 expression is a prognostic marker and may predict gemcitabine benefit in resected pancreatic cancer.

J Cancer, Volume 115, Issue 10 (2016) Keywords: Adaptor Proteins, Signal Transducing Adenocarcinoma Adult Aged Aged, 80 and over Antimetabolites, Antineoplastic Biomarkers, Tumor Calcium-Binding Proteins ...

Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.

Adjuvants, Immunologic Animals Antigens, Bacterial Cell Wall Humans Immunity, Innate Lectins, C-Type Models, Animal Mycobacterium Pathogen-Associated Molecular Pattern Molecules Protein Binding Signal ...

Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome.

Molecular Multienzyme Complexes Polyribonucleotide Nucleotidyltransferase Protein Binding Protein Conformation Protein Multimerization Pseudomonas aeruginosa Pseudomonas Phages RNA Helicases Viral Proteins ...

Molecular Analysis of Rising Fluoroquinolone Resistance in Belgian Non-Invasive Streptococcus pneumoniae Isolates (1995-2014).

Henry-Jean; Stéphane De Craeye; Verhaegen, Jan; Tulkens, Paul M; Vanhoof, Raymond Source: PLoS One, Volume 11, Issue 5, p.e0154816 (2016) Keywords: Amino Acid Substitution ATP-Binding Cassette Transporters ...

Human biomonitoring of heavy metals in the vicinity of non-ferrous metal plants in Ath, Belgium.

( = 106). We also studied subclinical health effects by quantifying retinol-binding protein and microalbuminuria, and by means of a Strengths and Difficulties Questionnaire. RESULTS: We obtained ...

Engineering a nanopore with co-chaperonin function.

functional elements with the nanopore, suggesting that emergent functions in molecular machines can be added bottom-up by incorporating modular elements into preexisting protein scaffolds. The binding of ...

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