Search results - 90 results

Development and validation of a microfluidic multiplex immunoassay for the determination of levels and avidity of serum antibodies to tetanus, diphtheria and pertussis antigens.

concentrations and binding kinetics (as a surrogate for avidity) of the IgG antibodies to the selected protein antigens. Overall, these findings show that this new Evalution pentaplex can accurately measure the ...

Evaluating SARS-CoV-2 spike and nucleocapsid proteins as targets for antibody detection in severe and mild COVID-19 cases using a Luminex bead-based assay.

a combination of the recombinant nucleocapsid protein (NP) and receptor-binding domain (RBD) results in highly specific (99 %) IgG antibody detection five months after infection in 96 % of cases. Although most ...

Development and application of a novel method to assess exposure levels of sensitizing and irritating substances leaching from menstrual hygiene products

sensitizers and irritants leaching from MHP s under simulated use conditions. To assess the leaching of chemicals from MHP s, a menstrual fluid simulant (MFS) simulating pH, osmolarity and protein binding was ...

Comprehensive toxicokinetic analysis reveals major interspecies differences in absorption, distribution and elimination of citrinin in pigs and broiler chickens

L/kg after IV administration). However, plasma protein binding did not differ statistically significant (91-98%). It is imperative to further investigate biotransformation and elimination pathways in ...

Y-box-binding protein 1 supports the early and late steps of HIV replication.

complete its replication cycle. In search for new therapeutic targets we identified the DNA and RNA binding protein Y-box-binding Protein 1 (YB-1) as a cofactor supporting early and late steps of HIV ...

The role of methylation, DNA polymorphisms and microRNAs on HLA-G expression in human embryonic stem cells.

and protein are present or absent in hESC. Several lines of evidence indicate that promoter CpG methylation and 3’ untranslated region (3’ UTR) polymorphisms may influence HLA-G expression. We ...

DLL4 expression is a prognostic marker and may predict gemcitabine benefit in resected pancreatic cancer.

Volume 115, Issue 10 (2016) Keywords: Adaptor Proteins, Signal Transducing Adenocarcinoma Adult Aged Aged, 80 and over Antimetabolites, Antineoplastic Biomarkers, Tumor Calcium-Binding Proteins Carcinoma, ...

Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.

Adjuvants, Immunologic Animals Antigens, Bacterial Cell Wall Humans Immunity, Innate Lectins, C-Type Models, Animal Mycobacterium Pathogen-Associated Molecular Pattern Molecules Protein Binding Signal ...

Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome.

Molecular Multienzyme Complexes Polyribonucleotide Nucleotidyltransferase Protein Binding Protein Conformation Protein Multimerization Pseudomonas aeruginosa Pseudomonas Phages RNA Helicases Viral Proteins ...

Molecular Analysis of Rising Fluoroquinolone Resistance in Belgian Non-Invasive Streptococcus pneumoniae Isolates (1995-2014).

Substitution ATP-Binding Cassette Transporters Bacterial Proteins Belgium DNA Gyrase Drug Resistance, Bacterial Female Fluoroquinolones Humans Longitudinal Studies Male Mutation, Missense Pneumococcal Infections ...

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