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Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK651

Metformin directly inhibited mTOR by enhancing PRAS40 ’s association with RAPTOR, whereas AICAR blocked the cell cycle through proteasomal degradation of the G2M phosphatase cdc25c. Together, our results ...

Highly pathogenic H5N1 influenza virus in smuggled Thai eagles, Belgium.

H5N1 Subtype Influenza in Birds Oseltamivir Phylogeny Raptors Thailand Abstract: We report the isolation and characterization of a highly pathogenic avian influenza A/ H5N1 virus from Crested Hawk-Eagles ...

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