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A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.

approximately 2,000. BPIP was inactive against the hepatitis C virus subgenomic replicon and yellow fever virus but demonstrated weak activity against GB virus. Drug-resistant mutants were at least 300-fold less ...

Use of the pAL5000 replicon in PAH-degrading mycobacteria: application for strain labelling and promoter probing.

PAH-derived fluorescence as assessed by confocal laser scanning microscopy. The results reported here demonstrate the suitability of the pAL5000 replicon for the development of recombinant DNA-based studies in ...

A rat model for hepatitis E virus.

Neoplasms mice Rats, Nude Replicon RNA, Messenger RNA, Viral RNA-Dependent RNA Polymerase Virus Replication Virus Shedding Abstract: Hepatitis E virus (HEV) is one of the prime causes of acute viral ...

ST131 fimH22 Escherichia coli isolate with a blaCMY-2/IncI1/ST12 plasmid obtained from a patient with bloodstream infection: highly similar to E. coli isolates of broiler origin.

 kb plasmid with blaCMY-2 from ESBL20160056 had an IncI1 replicon and belonged to ST12 using the plasmid MLST scheme. In total, 10 of the 14 ST131 E. coli isolates belonging to the fimH22 clade carried ...

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