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A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.
approximately 2,000. BPIP was inactive against the hepatitis C virus subgenomic replicon and yellow fever virus but demonstrated weak activity against GB virus. Drug-resistant mutants were at least 300-fold less ...
Use of the pAL5000 replicon in PAH-degrading mycobacteria: application for strain labelling and promoter probing.
PAH-derived fluorescence as assessed by confocal laser scanning microscopy. The results reported here demonstrate the suitability of the pAL5000 replicon for the development of recombinant DNA-based studies in ...