Search results - 64 results

Epidemiology and genotype 3 subtype dynamics of hepatitis E virus in Belgium, 2010 to 2017.

samples of suspected cases sent to the NRC between 2010 and 2017 were analysed for the presence of HEV-specific IgM and RNA. Virus was sequenced for genotyping and phylogenetic analysis in all samples ...

Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid

Source: Tuberculosis, Volume 117 (2019) Keywords: Delamanid Mycobacterium tuberculosis RNA sequencing Transciptomics Abstract: Tuberculosis (TB) is the most deadly infectious disease worldwide. To reduce TB ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

pump overexpression, and (d) ignore the multifactorial influence of compensatory mutations. Here, we introduce a next-generation diagnostic test based on quantification of antibiotic-specific RNA ...

Seasonal Genetic Drift of Human Influenza A Virus Quasispecies Revealed by Deep Sequencing

documented by consensus sequencing data. However, like other RNA viruses, influenza A viruses exist as a population of diverse, albeit related, viruses, or quasispecies. Interest in this quasispecies nature ...

Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.

Steven Van Gucht; Beyaert, R Source: J Virol (2018) Abstract: Rabies virus is a neurovirulent RNA virus, which causes about 59000 human deaths each year. Treatment for rabies does not exist due to ...

Preparing cDNA Libraries from Lytic Phage-Infected Cells for Whole Transcriptome Analysis by RNA-Seq.

Bacteriophage RNA-seq Abstract: Whole genome wide analysis of transcription using RNA-Seq methods is a powerful way to elucidate differential expression of gene features in bacteria across different conditions as ...

Y-box-binding protein 1 supports the early and late steps of HIV replication.

complete its replication cycle. In search for new therapeutic targets we identified the DNA and RNA binding protein Y-box-binding Protein 1 (YB-1) as a cofactor supporting early and late steps of HIV ...

Complete coding sequence of a novel picorna-like virus in a blackbird infected with Usutu virus.

Picornaviridae Infections Plants whole genome sequencing Abstract: Using random high-throughput RNA sequencing, the complete coding sequence of a novel picorna-like virus (a 9,228-nt contig containing 212,202 ...

Clinical burden of hepatitis E virus infection in a tertiary care center in Flanders, Belgium.

tertiary care center in Flanders, Belgium. STUDY DESIGN: In the setting of Ghent University Hospital, patients were assessed for the presence of HEV IgG and IgM as well as HEV RNA if no other cause was found ...

Susceptibility of Pigs to Zoonotic Hepatitis E Virus Genotype 3 Isolated from a Wild Boar.

four groups inoculated with a WbHEV strain, a WbHEV strain previously passaged in swine, a swine HEV strain or a HEV-negative swine liver homogenate. After intravenous inoculation, HEV RNA was detected ...

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