Search results - 564 results
Angiotensin IV displays only low affinity for native insulin-regulated aminopeptidase (IRAP).
from proteolytic degradation, the aminopeptidase N selective inhibitor '7B' only exerts the latter effect. By using 7B along with the new stable Ang IV-analog [(3) H] AL-11, we here show that ...
Orthogonal chromatographic descriptors for modelling caco-2 drug permeability
systems, those found dissimilar for the used data set were selected. The retention factors on these systems were then used as descriptors in QSAR modelling. Modelling was performed using Stepwise Multiple ...
Differential modulations of striatal tyrosine hydroxylase and dopamine metabolism by cannabinoid agonists as evidence for functional selectivity in vivo.
Number 2336, p.2328- 2336 (2012) Keywords: access Activity Adult Agonist-selective coupling an analysi analysis AS brain cause CB1 cannabinoid receptor Control data Dopamine DRUG effect effects evidence ...
Scientific Opinion of the EFSA Panel on Plant Protection Products and their Residues (PPR) on the science behind the guidance for scenario selection and scenario parametrisation for predicting environmental concentrations of plant protection product...
plant plant protection product PROCESSES PRODUCTS Regulatory Residue revision Science Selection SOFTWARE Soil specific State System use WATER Abstract: Based on consultation with Member States, EFSA asked ...
Potential of Mycobacterium tuberculosis resuscitation-promoting factors as antigens in novel tuberculosis sub-unit vaccines.
that Rv1009 (rpfB) and Rv2389c (rpfD) are the most antigenic in the tested models. We therefore selected rpfB and rpfD for testing their vaccine potential as plasmid DNA vaccines. Elevated cellular ...
Enhanced analysis of real-time PCR data by using a variable efficiency model: FPK-PCR.
implementing a global efficiency model, reproducibility is improved as the selection of a window of application is avoided. Health Topics: Quality of healthcare Category: A1 FOS Classification: 3.03 Health ...
Genetic characterization of low pathogenic H5N1 and co-circulating avian influenza viruses in wild mallards (Anas platyrhynchos) in Belgium, 2008.
H1N1, H4N6, H5N1, H5N3, and H10N7). A LP H5N1 and two co-circulating (same location, same time period) viruses were selected for full genome sequencing. An H1N1 (A/Anas platyrhynchos/Belgium/09-762/2008) ...
Development and inter-laboratory validation study of an improved new real-time PCR assay with internal control for detection and laboratory diagnosis of African swine fever virus.
a TaqMan(®) probe specific for ASFV were selected from conserved regions of the p72 gene. The limit of detection of the new real-time PCR assay is 5.7-57 copies of the ASFV genome. High accuracy, ...
Nucleotide polymorphism-based single-tube test for robust molecular identification of all currently described Brucella species.
a ligase chain reaction (LCR)-based method that simultaneously assesses multiple genetic markers at the single-nucleotide level. Most of the selected markers originate from a multilocus sequence typing ...
International collaborative study on the occurrence of plasmid-mediated quinolone resistance in Salmonella enterica and Escherichia coli isolated from animals, humans, food and the environment in 13 European countries36580
Studies Salmonella Salmonella enterica Salmonella Infections Salmonella Infections,Animal SB- IM SCREENING SELECTED Selection Sequence Analysis Sequence Analysis,DNA study The Netherlands values veterinary ...