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Culture filtrate specific H-2(b) restricted CD8+ T cells activated in vivo by Mycobacterium tuberculosis or bovis BCG recognize a restricted number of immunodominant peptides.
restricted CD8 + cytolytic T lymphocyte (CTL) recognizing target cells incubated with mycobacterial culture filtrate. Here, we show that in vitro restimulation of spleen cells from BCG vaccinated or ...
Morbillivirus in common seals stranded on the coasts of Belgium and northern France during summer 1998.
was observed in a few lymphocytes in the spleen and lymph nodes of three seals. Anti- CDV neutralising antibodies were detected in sera from six animals. Seven of the seals were positive by reverse ...
Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting.
interferon (IFN-gamma) response in spleen two- to fourfold. Further, intracellular cytokine analysis by flow cytometry also showed an increase in IFN-gamma-producing CD4 (+) T cells in ...
CD4+ T cells contain Mycobacterium tuberculosis infection in the absence of CD8+ T cells in mice vaccinated with DNA encoding Ag85A.
cytokines similar to wild-type mice. Although beta2m-/- mice were more susceptible to M. tuberculosis infection, following vaccination they efficiently controlled bacterial replication in spleen and lungs ...
Distinct VH repertoires in primary and secondary B cell lymphocyte subsets in the preimmune repertoire of A/J mice: the CRI-A idiotype is preferentially associated with the HSA(low) B cell subset.
of CRI-A transcripts is associated with the HSA (low) compartment, while CRI-C transcripts are mainly associated with HSA (high) B cell subsets. This has been demonstrated with spleen cells of adult ...
Tuberculosis DNA vaccine encoding Ag85A is immunogenic and protective when administered by intramuscular needle injection but not by epidermal gene gun bombardment.
Interleukin-4 Lung mice Mice, Inbred BALB C Mice, Inbred C57BL Mycobacterium tuberculosis Spleen T-Lymphocytes, Cytotoxic Tuberculosis Vaccination Vaccines, DNA Abstract: Immunogenicity and protective efficacy of ...
Classical swine fever virus: a ring test to evaluate RT-PCR detection methods.
viral RNA representative of seven different genetic subtypes of CSFV. The other set comprised 40 clinical samples containing tonsil, spleen, whole blood or serum from a pig that had been experimentally ...
Cloning of the gene encoding a 22-kilodalton cell surface antigen of Mycobacterium bovis BCG and analysis of its potential for DNA vaccination against tuberculosis.
p.1040-7 (2000) Keywords: Animals Antigens, Bacterial BCG Vaccine Cloning, Molecular Cytokines mice Mice, Inbred BALB C Mice, Inbred C57BL Molecular Weight Vaccines, DNA Abstract: Using spleen cells from ...
Comparison of biological activities of natural and recombinant chicken interferon-gamma.
Proteins Spleen Spodoptera Abstract: In recent years, chicken interferon-gamma (ChIFN-gamma) has been identified and cloned from a chicken T cell line. In this study, recombinant ChIFN-gammma produced in the ...
Development of immunocompetence of broiler chickens.
demonstrated by immunohistochemical staining early in the development of chicken spleen. However, the typical structures of the spleen, such as the peri-arteriolar lymphoid sheath (PALS) and the ellipsoids with ...