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Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting.

interferon (IFN-gamma) response in spleen two- to fourfold. Further, intracellular cytokine analysis by flow cytometry also showed an increase in IFN-gamma-producing CD4 (+) T cells in ...

Tuberculosis DNA vaccine encoding Ag85A is immunogenic and protective when administered by intramuscular needle injection but not by epidermal gene gun bombardment.

Interleukin-4 Lung mice Mice, Inbred BALB C Mice, Inbred C57BL Mycobacterium tuberculosis Spleen T-Lymphocytes, Cytotoxic Tuberculosis Vaccination Vaccines, DNA Abstract: Immunogenicity and protective efficacy of ...

Cloning of the gene encoding a 22-kilodalton cell surface antigen of Mycobacterium bovis BCG and analysis of its potential for DNA vaccination against tuberculosis.

p.1040-7 (2000) Keywords: Animals Antigens, Bacterial BCG Vaccine Cloning, Molecular Cytokines mice Mice, Inbred BALB C Mice, Inbred C57BL Molecular Weight Vaccines, DNA Abstract: Using spleen cells from ...

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