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Falsification of biotechnology drugs: current dangers and/or future disasters?

falsified medical products in the developed world. In recent years, also biotechnology drugs (synthetic peptide drugs and protein drugs) have been reported to be prone for falsifications. Next to the ...

Short-term biodistribution and clearance of intravenously administered silica nanoparticles

Yves-Jacques; Ann Ruttens; S. Roels Source: Toxicology Reports, Volume 5, Number 638 (2018) Keywords: distribution in vivo intravenous exposure nanomaterials synthetic amorphous silica Abstract: Recently, ...

Impurity profiling of the most frequently encountered falsified polypeptide drugs on the Belgian market

Volume 188, Number 807 (2018) Abstract: Advances in biotechnology and the chemical synthesis of peptides have made biopharmaceuticals and synthetic peptide drugs viable pharmaceutical compounds today and ...

Chemometrics and chromatographic fingerprints to classify plant food supplements according to the content of regulated plants.

supplements are gaining popularity, resulting in a broader spectrum of available products and an increased consumption. Next to the problem of adulteration of these products with synthetic drugs the presence of ...

Detection of regulated herbs and plants in plant food supplements and traditional medicines using infrared spectroscopy.

identification of a specific toxic or regulated plant in herbal preparations or plant food supplements is a real challenge, since they are often powdered, mixed with other herbal or synthetic powders and ...

Laboratory validation of two real-time RT-PCR methods with 5'-tailed primers for an enhanced detection of foot-and-mouth disease virus.

purposes, both assays were run in parallel in a triplex one-step RT-qPCR protocol with beta-actin as an internal control and synthetic RNA as an external control. We obtained low limits of detection and high ...

Inflammatory Properties and Adjuvant Potential of Synthetic Glycolipids Homologous to Mycolate Esters of the Cell Wall of Mycobacterium tuberculosis.

health Public-health Receptor response Responses result results Service Species strain structure study sugar Synthetic System TDM Term Tuberculosis vaccine vaccines WIV-ISP Abstract: The cell wall of ...

Characterization of two recombinant HVT-IBD vaccines by VP2 insert detection and cell-mediated immunity after vaccination of specific pathogen-free chickens.

Diseases Specific Pathogen-Free Organisms Vaccination Vaccines, Synthetic Viral Structural Proteins Viral Vaccines Abstract: Infectious bursal disease (IBD) is an avian viral disease that causes severe ...

Mycobacterium tuberculosis-associated synthetic mycolates differentially exert immune stimulatory adjuvant activity

School South Africa SOUTH-AFRICA structure study Synthetic Tuberculosis United Kingdom United-kingdom Universities university Abstract: Mycolic acids (MA s) are highly hydrophobic long-chain alpha-alkyl ...

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