Search results - 127 results

Development of novel analytical methods to trace small micro- and nanoplastics in food matrices

larger MP s in terms of occurrence, distribution, quantification, and toxicological effects on humans identifying food as their main intake source. Nowadays, research interest is going towards MP s with ...

The 3Rs Principle in the field of toxicology

diseases within the One Health concept”, COST, Issue COST, Online Workshop (2023) Keywords: 3Rs animal testing RE-Place Toxicology Service:  Risques chimiques et physiques pour la santé Chemische en fysische ...

Improving health and environmental chemical hazard and risk assessment practices in Belgium

chemicals Ecotoxicology environment hazard health Risk Assessment Safety assessment Toxicology Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des ...

Challenges in Drug Surveillance: Strengthening the Analysis of New Psychoactive Substances by Harmonizing Drug Checking Services in Proficiency Testing.

consumption. However, NPS cause a toxicological battle for the researchers, as factors such as the unpredictability and quick shift of the market complicate the detection. METHODS: To evaluate challenges posed ...

The contribution of cacao consumption to the bioaccessible dietary cadmium exposure in the Belgian population

Toxicology, Volume 172 (2023) Keywords: bioaccessibility Cadmium chocolate consumption survey Abstract: Since 2019, EU limits apply to cadmium (Cd) concentrations in cacao-derived food products. The dietary ...

Regulatory safety assessment of nanoparticles for the food chain in Europe

characterisation are required with special provisions. In particular, certain nano-specific considerations are highlighted that have to be considered during toxicological testing with the aim to demonstrate consumer ...

Novel prediction models for genotoxicity based on biomarker genes in human HepaRGTM cells

genetic toxicology GENOMARK biomarker predictive toxicology human health risk assessment new approach methodologies (NAMs) Abstract: Transcriptomics-based biomarkers are promising new approach methodologies ...

Modeling the migration of chemicals from food contact materials to food: The MERLIN-expo/VERMEER toolbox.

simulations showed a good match between predicted and experimental values. The tested models can be used to provide insights in the amount and the type of toxicological data that are needed for the safety ...

In Silico Methods for Chromosome Damage.

Keywords: Chromosome Aberrations Chromosomes DNA Damage Humans Mutagenicity Tests Mutagens Mutation Abstract: Due to the link with serious adverse health effects, genotoxicity is an important toxicological ...

RE-Place: A Unique Project Collecting Expertise on New Approach Methodologies

Publication Type: Peer reviewed scientific article Authors: Mieke Van Mulders; Nancy Liodo; Birgit Mertens; Vera Rogiers Source: Frontiers in Pharmacology: Predictive Toxicology (2022) Keywords: 3Rs ...

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