Search results - 134 results

Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health.

data sets are available for altersetin (ALS), altenuene (ALT), and tentoxin (TEN). The occurrence and toxicological relevance of perylene quinone-based Alternaria toxins still remain to be fully ...

Pollutant exposure and myocardial injury: Protocol and progress report for a toxicological systematic mapping review.

toxicological evidence is needed. This protocol outlines a step-by-step framework for conducting this review. Using the National Toxicology Program (NTP) Health Assessment and Translation (HAT) approach for ...

Development of novel analytical methods to trace small micro- and nanoplastics in food matrices

larger MP s in terms of occurrence, distribution, quantification, and toxicological effects on humans identifying food as their main intake source. Nowadays, research interest is going towards MP s with ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Birgit Mertens Source: 57th Congress of the European Societies of Toxicology, Ljubljana, Slovenia (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to testing and assessment ...

Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals

Source: 57th Congress of the European Societies of Toxicology (Eurotox 2023), Ljubljana, Slovenia (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health ...

The SILIFOOD application: a new tool to support risk assessment of non-evaluated food contact materials substances

Manganaro; Els Van Hoeck; Birgit Mertens Source: 57th Congress of the European Societies of Toxicology (Eurotox 2023), Ljubljana, Slovenia (2023) Keywords: Chemical risk assessment food contact materials QSAR ...

The 3Rs Principle in the field of toxicology

diseases within the One Health concept”, COST, Issue COST, Online Workshop (2023) Keywords: 3Rs animal testing RE-Place Toxicology Service:  Risques chimiques et physiques pour la santé Chemische en fysische ...

A Systematic Review on Pollutant Induced Cardiotoxicity: Providing a Toxicological Foundation for NAM Development and Regulatory Acceptance

Ritskes-Hoitinga; R. Gehring Source: 12th World Congress on Alternatives and Animal Use in the Life Sciences, Nigara falls, Canada (2023) Keywords: Cardiotoxicity pollutants systematic review toxicological evidence ...

Improving health and environmental chemical hazard and risk assessment practices in Belgium

chemicals Ecotoxicology environment hazard health Risk Assessment Safety assessment Toxicology Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des ...

Challenges in Drug Surveillance: Strengthening the Analysis of New Psychoactive Substances by Harmonizing Drug Checking Services in Proficiency Testing.

consumption. However, NPS cause a toxicological battle for the researchers, as factors such as the unpredictability and quick shift of the market complicate the detection. METHODS: To evaluate challenges posed ...

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