Search results - 19 results

Increasing the Vaccine Potential of Live M. bovis BCG by Coadministration with Plasmid DNA Encoding a Tuberculosis Prototype Antigen.

Bacille-Calmette-Guérin (BCG) is still the sole vaccine used against tuberculosis, but confers only variable efficacy against adult pulmonary tuberculosis (TB). Though no clear explanation for this limited efficacy has ...

The geographic diversity of nontuberculous mycobacteria isolated from pulmonary samples: an NTM-NET collaborative study36500

Laboratories List M Mycobacterium Mycobacterium avium Complex Network Nontuberculous Mycobacteria observed Patient patients Pulmonary relative result results Sample Samples SB- IM study Tuberculosis Abstract: ...

Mice genetically inactivated in interleukin-17A receptor are defective in long-term control of Mycobacterium tuberculosis infection.

of M. tuberculosis infection, as demonstrated by a progressively increasing pulmonary bacterial burden and shortened survival time. Compared with infected wild-type mice, IL- 17RA (-/-) mice showed ...

Mucosal and systemic immune responses to Mycobacterium tuberculosis antigen 85A following its co-delivery with CpG, MPLA or LTB to the lungs in mice1377

H37R v. In conclusion, CpG and MPLA were found to be potential adjuvants for pulmonary vaccination against tuberculosis, providing Th-1 and Th-17 immune responses and a good safety profile Service:  ...

M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.

pulmonary form of TB, which often results from the reactivation of a latent M. tuberculosis (M.tb)infection. Among the new approaches in TB vaccine development, live attenuated M.tb mutants are a promising ...

Clinical value of IS6110-based loop-mediated isothermal amplification for detection of Mycobacterium tuberculosis complex in respiratory specimens

specificity sputum study Technique Test tests Therapy tolerance Tuberculosis Tuberculosis,Pulmonary Universities university Abstract: OBJECTIVES: A fundamental to global tuberculosis (TB) control is timely and ...

Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary delivery34028

production protection Pulmonary Ratio Research Research Support residence response Responses SAFETY SB- IM specific Spleen study Target Targets time Tuberculosis Vaccination vaccine Abstract: The current ...

Lymph node targeting of BCG vaccines amplifies CD4 and CD8 T-cell responses and protection against Mycobacterium tuberculosis34032

tuberculosis Objective pathogenicity prevention & control problems production protection Pulmonary recombinant Research Research Support response Responses risk SB- IM secretion Strategies Strategy study ...

Mycobacterium tuberculosis infection induces hypoxic lung lesions in the rat36548

Research Research Support resistance result results SB- IM State Tension Tuberculosis Tuberculosis,Pulmonary use Abstract: Hypoxia is believed to influence the metabolic state of Mycobacterium tuberculosis ...

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